Protein Alignment STX7 and Syx17

DIOPT Version :9

• Sequence 1: NP_001313507.1
• Gene: STX7 / 8417
• HGNCID: 11442
• Length: 261
• Species: Homo sapiens
• Sequence 2: NP_001261414.1
• Gene: Syx17 / 38541
• FlyBaseID: FBgn0035540
• Length: 346
• Species: Drosophila melanogaster
• Alignment Length: 236
• Identity: 47/236 - (19%)
• Similarity: 96/236 - (40%)
• Gaps: 49/236 - (20%)

Human    25 ITQCSVEIQRTLNQLGTPQDSPELR---------------QQLQQKQQYTNQLAKETDKYIKEFG 74
            :.|..|.||| ...:..|.....|:               |::::::....::.|:....:.|..
  Fly     9 LKQAEVSIQR-FQDVAVPHHLSLLKNHRSNIEKSLALGDWQKIKKEELNAMRVIKQIKNLLLEMD 72

Human    75 SLPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAERE----KEFVARVRAS--SRVSGSFP 133
            :|        :.|::::        .|..|..:.:...:..    |||......|  |.:|..:.
  Fly    73 AL--------REKVREE--------DLERFDDLMKPGRDTAFAGMKEFAELQLKSPTSTLSSQYD 121

Human   134 EDSSKERNLVSWES----QTQPQVQVQDEEITEDDLRLIHERESSIRQLE---ADIMDINEIFKD 191
            :|...:...|...|    :..||:|: :.::.|..|.   :|::.:.|:|   .:|.|::.:|:.
  Fly   122 DDLDNQPQEVDMNSLPAHRHMPQLQL-NFQLEEHQLA---QRQACLDQMENLQQEIYDLHGMFQG 182

Human   192 LGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQR 232
            :..:..||...::.|..|.|.|..:|||....|.||..|::
  Fly   183 MRQLTAEQSVAVEKIADNAEEALENVQQGELNLRRALTYKK 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STX7	NP_001313507.1	Syntaxin_2	18..119	CDD:373109	16/112 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..148		4/22 (18%)
		SNARE_syntaxin7	168..227	CDD:277228	16/61 (26%)
Syx17	NP_001261414.1	SNARE_syntaxin17	156..217	CDD:277199	17/63 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910