Protein Alignment STX7 and syx-7

DIOPT Version :10

• Sequence 1: NP_003560.2
• Gene: STX7 / 8417
• HGNCID: 11442
• Length: 261
• Species: Homo sapiens
• Sequence 2: NP_492422.2
• Gene: syx-7 / 172718
• WormBaseID: WBGene00009478
• Length: 248
• Species: Caenorhabditis elegans
• Alignment Length: 245
• Identity: 72/245 - (29%)
• Similarity: 143/245 - (58%)
• Gaps: 16/245 - (6%)

Human    13 QLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQL-QQKQQYTNQLAKETDKYIKEFGSL 76
            :.|.::..|||.:.|..::::..:..|....:|.:..::| .:|.....:|:|||:..:|..  :
 Worm    10 ETASQLQLNIQNLNQQVIQLESFITNLSDSSESGQRERELFNRKAHNAQELSKETNALLKRL--V 72

Human    77 PTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGSFPEDSSKERN 141
            ..:.|::..|.: ::||..|:...|...|..||:||:.||..:......::.:    .|:: |.:
 Worm    73 VMSNSDKNLRGV-RERLQNEYIGVLNRLQASQRKAAQTEKAGMVAAEMDAQAA----RDAA-EYD 131

Human   142 LVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSI 206
            :.....::..|:|:..::  :.:|:.:.||:::::|||.||.|:|.||.:|..::|||||::|||
 Worm   132 MYGNNGRSGGQMQMTAQQ--QGNLQDMKERQNALQQLERDIGDVNAIFAELANIVHEQGDMVDSI 194

Human   207 EANVENAEVHVQQANQQLSRAADYQRKSRK----TLC-IIILILVIGVAI 251
            |||||:|:::|:|..|.:.:|..|.:|:|:    .|| .:|||.:||:.:
 Worm   195 EANVEHAQIYVEQGAQNVQQAVYYNQKARQKKLLLLCFFVILIFIIGLTL 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STX7	NP_003560.2	Syntaxin_2	18..119	CDD:464199	26/101 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..148		2/18 (11%)
		SNARE_syntaxin7	168..227	CDD:277228	29/58 (50%)
syx-7	NP_492422.2	SynN	3..111	CDD:214699	25/103 (24%)
		SNARE_syntaxin7_like	156..215	CDD:277200	29/58 (50%)