Protein Alignment ARL6 and Arl4

DIOPT Version :10

• Sequence 1: NP_001310442.1
• Gene: ARL6 / 84100
• HGNCID: 13210
• Length: 193
• Species: Homo sapiens
• Sequence 2: NP_001245408.1
• Gene: Arl4 / 43771
• FlyBaseID: FBgn0039889
• Length: 313
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 73/280 - (26%)
• Similarity: 106/280 - (37%)
• Gaps: 118/280 - (42%)

Human    18 VHVLCLGLDNSGKTTIINKLKPSNAQSQNILPTIGFSIEKF-----KSSSLSFTVFDMSGQGRYR 77
            :||:.||||::||||.:.:||..  |..|.:|||||:.||.     |:..:.|.|:|:.||.:.|
  Fly    26 LHVVMLGLDSAGKTTALYRLKFD--QYLNTVPTIGFNCEKVQCTLGKAKGVHFLVWDVGGQEKLR 88

Human    78 NLWEHYYKEGQAIIFVIDSSDRLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDAVTSVK 142
            .||..|.:....|:|||||.|..||..||.||......||  ::.:|:|..|||.||.:|..:::
  Fly    89 PLWRSYTRCTDGILFVIDSVDTERMEEAKMELMRTAKCPD--NQGVPVLILANKQDLPNACGAME 151

Human   143 VSQLLCL-------------------------------ENIKDKP-------------------- 156
            :.:||.|                               ::|.||.
  Fly   152 LEKLLGLNELYNPVPNISMPSSSDSSPTINLIGCRVSNQSITDKSLEEKKESHLHSSMIHIKPAL 216

Human   157 ----------------------------------------------------------WHICASD 163
                                                                      |:|..:.
  Fly   217 ESKDHNSTLSGGALTAFIYPQSHNNSAVLDQKNPQDVKNGFHNKKMNRSSSNSVQFRGWYIQPTC 281

Human   164 AIKGEGLQEGVDWLQEKTIQ 183
            ||.|||||||:|.|.:..::
  Fly   282 AITGEGLQEGLDALYDMILK 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARL6	NP_001310442.1	Arl6	19..180	CDD:206722	73/274 (27%)
Arl4	NP_001245408.1	P-loop containing Nucleoside Triphosphate Hydrolases	24..311	CDD:476819	73/280 (26%)