Protein Alignment MYCBPAP and CG33140

DIOPT Version :10

• Sequence 1: XP_016880694.1
• Gene: MYCBPAP / 84073
• HGNCID: 19677
• Length: 1011
• Species: Homo sapiens
• Sequence 2: NP_788279.1
• Gene: CG33140 / 35642
• FlyBaseID: FBgn0053140
• Length: 720
• Species: Drosophila melanogaster
• Alignment Length: 727
• Identity: 139/727 - (19%)
• Similarity: 236/727 - (32%)
• Gaps: 222/727 - (30%)

Human   236 KQKAPKEEKRPPWAPPPQHNFLKNWQRNTALRKKQQEALSEHLKKPVSELLMHTGETY--RRIQE 298
            |::.|..:||           |:.|:.....||..||.:.....|..||:|.:...|.  |..|.
  Fly    91 KEREPHVDKR-----------LRYWKEVLHQRKLMQERVQRETGKLASEVLFNRRSTLDNRDGQM 144

Human   299 ERELIDCTLPTRRDRKSWENSGFWSRLEYLGDEM--------TGLVMTKTKTQRGLMEPITHIRK 355
            .:.::|..     ||...|.. ..:.|..|||::        .||..|..|.::...:.:..:..
  Fly   145 VKRVLDYA-----DRMKGERL-MSAPLSKLGDQLDPCTCQVVPGLQATTPKAEKVGYKDLEIVGM 203

Human   356 PHSIRVETGLPAQRDASYRYTWDRSLFLIYRRK----ELQRIMEELDFSQQDIDGLEVVGKGW-- 414
            |...:.|.......:......|.:|.||..|.:    ::|.::|..    .|:|.|:|.|...
  Fly   204 PEVCKTEILGKEAMEQDPPPGWLQSEFLDKRLEQNFVDIQNVVEFF----PDVDALQVKGTALSK 264

Human   415 ------PFSAVTVEDYTVFERSQ--------------GSSSEDTAYLGTLASSSDVSMPILGPSL 459
                  || .|.|:......:|:              |.:.|.::  ||.....||.:.:.|...
  Fly   265 INRLPKPF-LVDVDSMHTVTKSESSPICTEECICESCGETEEKSS--GTPPPIPDVGLRVNGVDY 326

Human   460 LFCGKPACWIRGSNPQDKRQVGIAAHLTFETLEGEKTSSELTVVNNGTVAIWYDWRRQHQPDTFQ 524
            :.|       .|.....|....|.|..|.:..: .:....|.:.|.||.::.:.|::........
  Fly   327 VPC-------EGDGGGIKDCYEIVARFTCDPFQ-RRLKHVLQLTNIGTQSLSFSWKQSTYYYNRG 383

Human   525 DLKKNRMQRFYFDNREGVILP-GEIKTFTFFFKSLTAGVFREFWEFRTHPTLLGGAILQVNLHAV 588
            .|...:...|:|| .||..|. ||.:.....::.....:..|.|..:..|.:..|....:.|...
  Fly   384 SLLLAQDNEFHFD-LEGFRLSHGETRNVAVLYQPRKVAMAVELWLLQVEPRIFCGRQESLLLRLY 447

Human   589 SLTQDVFEDERKVLE--------------SKLTAHEAVTVVREVLQELLMGVLTPERTPSPV--- 636
            .......:...|:||              .|||.|              :|.|.|...|.|.
  Fly   448 GRCTPPADYMAKLLECQCVCICKSDAVEMDKLTTH--------------LGALAPMVVPPPTCCP 498

Human   637 -DAYLTEEDLFRHRNPPLHY------EHQVVQSLHQLWRQYMTLPAKAEEARPGDKEHVSPIATE 694
             :..|.:.:.|...||  .|      :.:|:::.||
  Fly   499 YERPLDDREAFNALNP--GYICARFDDLEVLRAFHQ----------------------------- 532

Human   695 KASVNAELLPRFRSPISETQVPRPENEALRESGSQKARVGTKSPQRKSIMEE---ILVEESPDVD 756
                   .|.:.|.|:.:.::...::..:|.:|         ..:|:||..|   :|.
  Fly   533 -------RLKKPREPLWDMRLSTIKDYIMRING---------LVERESIFSEFNQLLA------- 574

Human   757 STKSPWEPDGLPLLEWNLCLEDFRKAVMVLPDENHREDALMRLNKAALELCQKPRPLQSNLLHQM 821
                       |||...                       ..||.::.:..||.|.....:...:
  Fly   575 -----------PLLGGG-----------------------FSLNASSQQDVQKQRSRFIYVRGVI 605

Human   822 C--LQLWRDVI----DSLVGHSM--WLRSVLGLPEKETIYLNVPEEQDQKSP--PI-----MEVK 871
            |  :..|.|::    ||.....:  :.:|:||..|:     ...||.||..|  ||     ||:
  Fly   606 CNGIAEWEDLMFNVEDSFFKPELQRYYQSLLGESEE-----GDEEEPDQPKPMTPIDMEKLMEI- 664

Human   872 VPVGKAGKEERK 883
              :|:...:|:|
  Fly   665 --LGETELDEKK 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYCBPAP	XP_016880694.1	MYCBPAP	251..670	CDD:464234	96/479 (20%)
CG33140	NP_788279.1	MYCBPAP	95..534	CDD:464234	99/523 (19%)