DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AT1G35625 and IRC20

DIOPT Version :9

Sequence 1:	NP_001319153.1	Gene:	AT1G35625 / 840462	AraportID:	AT1G35625	Length:	318	Species:	Arabidopsis thaliana
Sequence 2:	NP_013348.1	Gene:	IRC20 / 850949	SGDID:	S000004237	Length:	1556	Species:	Saccharomyces cerevisiae

Alignment Length:	200	Identity:	46/200 - (23%)
Similarity:	80/200 - (40%)	Gaps:	55/200 - (27%)

- Green bases have known domain annotations that are detailed below.

plant    93 IRNAQEAGYKAAIVYNDRYEELLVRMAGNSSGVYIHGVLVTRTSGEVLKE-YTSRAEMELLLIPG 156
            :|....:....:.:.|  :|:.|::....|..::.:...| |.|.::|.. |.::.|.
Yeast  1116 VRRISSSNESESTIQN--FEDYLLQYEVESKSLFKYNKQV-RESLKILGSIYNAKTEY------- 1170

plant   157 FGISSWSIMAITFVSLLVISAVLASYFSVRRHRIRQHVRDLHHGG----------------QGHS 205
              .|....::.:.|||..:||...|      |.||...:.|  ||                :..|
Yeast  1171 --YSQLQRISDSLVSLHSLSAPQLS------HLIRTINKSL--GGTLDAKINNIESRLIYLKNLS 1225

plant   206 RMPKDLLQSMPTEVYTGVLEEGSTSVTCAICIDDYRVGEILRILPCKHKYHAVCIDSWLGRCRSF 270
            |: ||.|..             :..::|:||:.:..:|.|::   |.|.:...||.:|| |..|.
Yeast  1226 RL-KDTLND-------------NQILSCSICLGEVEIGAIIK---CGHYFCKSCILTWL-RAHSK 1272

plant   271 CPVCK 275
            ||:||
Yeast  1273 CPICK 1277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AT1G35625	NP_001319153.1	None
IRC20	NP_013348.1	HepA	172..>568	CDD:223627
		DEXQc_SHPRH	383..602	CDD:350828
		RAD18	1234..>1327	CDD:227719	16/47 (34%)
		RING-HC_RNF10	1239..1276	CDD:319450	15/40 (38%)
		SF2_C_SNF	1356..1485	CDD:350180
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	49	1.000	Domainoid score	I3077
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000