DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AT1G35625 and RNF167

DIOPT Version :9

Sequence 1:	NP_001319153.1	Gene:	AT1G35625 / 840462	AraportID:	AT1G35625	Length:	318	Species:	Arabidopsis thaliana
Sequence 2:	NP_001357232.1	Gene:	RNF167 / 26001	HGNCID:	24544	Length:	374	Species:	Homo sapiens

Alignment Length:	342	Identity:	105/342 - (30%)
Similarity:	147/342 - (42%)	Gaps:	76/342 - (22%)

- Green bases have known domain annotations that are detailed below.

plant    28 NTFLSFDDVEANFTPVVRRSGEYGLLYAAEPLDACSYLT---NMAEKGSKFRPSYVLIVRGGCSF 89
            |..:.|.|:.|.|...:.:.|..|.|..|.|.:|||.:.   .....||.|   ..|:.|..|:|
Human    33 NASMDFADLPALFGATLSQEGLQGFLVEAHPDNACSPIAPPPPAPVNGSVF---IALLRRFDCNF 94

plant    90 EEKIRNAQEAGYKAAIVYNDRYEELLVRMAGNS----SGVYIHGVLVTRTSGEVLKE-YTSRAEM 149
            :.|:.|||:|||.||:|:|....||| .|..||    ..::|..|.:...|.|.|:. :......
Human    95 DLKVLNAQKAGYGAAVVHNVNSNELL-NMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGA 158

plant   150 ELLLIPG--FGISSWSIMAITFVSLLVIS--AVLASYFSVRRHRIRQHVRDLHHGGQGHSRMPKD 210
            .:||:|.  |.:..:.|.....|.|||::  ||:.:       |..||.:.|.     .:|:.|:
Human   159 RVLLVPDNTFPLGYYLIPFTGIVGLLVLAMGAVMIA-------RCIQHRKRLQ-----RNRLTKE 211

plant   211 LLQSMPTEVYTGVLEE--------------------GSTSVTCAICIDDYRVGEILRILPCKHKY 255
            .|:.:||..|...|..                    |.....||||:|:|..|:.||:|||.|.|
Human   212 QLKQIPTHDYQKALNSSMFCPDLILPTCLISSTGFVGDQYDVCAICLDEYEDGDKLRVLPCAHAY 276

plant   256 HAVCIDSWLGRCRSFCPVCKQ------------------------NPRTGNDVPPASETTPLISP 296
            |:.|:|.||.:.|..||:|||                        .||.    .||||.|||:..
Human   277 HSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEGDEGEPRD----HPASERTPLLGS 337

plant   297 GPNSITSLQSFYDLPIV 313
            .|...||..|....|:|
Human   338 SPTLPTSFGSLAPAPLV 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AT1G35625	NP_001319153.1	None
RNF167	NP_001357232.1	PA_C_RZF_like	20..170	CDD:239038	46/140 (33%)
		RING-H2_RNF167	252..297	CDD:319711	23/44 (52%)
		RING-H2 finger (C3H2C3-type)	254..295	CDD:319711	22/40 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	71	1.000	Domainoid score	I4059
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I2220
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	1	1.000	-	-		mtm1436
orthoMCL	1	0.900	-	-		OOG6_103040
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.770