DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AT1G35625 and C18B12.4

DIOPT Version :9

Sequence 1:	NP_001319153.1	Gene:	AT1G35625 / 840462	AraportID:	AT1G35625	Length:	318	Species:	Arabidopsis thaliana
Sequence 2:	NP_510498.1	Gene:	C18B12.4 / 181600	WormBaseID:	WBGene00007666	Length:	456	Species:	Caenorhabditis elegans

Alignment Length:	280	Identity:	71/280 - (25%)
Similarity:	120/280 - (42%)	Gaps:	45/280 - (16%)

- Green bases have known domain annotations that are detailed below.

plant    57 EPLDACSYLTNMAEKGSKFRPSYVLIVRGG----CSFEEKIRNAQEAGY--KAAIVYNDRYEELL 115
            ||:|||..:.......::....:..:.|..    |.|..:....|.:.|  :..|.||...:| .
Worm    74 EPVDACGPVRIAQNHTTRCHNLFAFVSRSNISHPCKFSHQAFMVQNSTYPFRLVIFYNYPGQE-P 137

plant   116 VRMAGNS--SGVYIHGVLVTRT-SGEVLKEYTSRA--EMELLLIPGFGISSWSIMAITFVSLLVI 175
            :.|.|..  ..|.|..::::.. ..|:.|:::..|  .:.:.:.||:    :.:.......|:||
Worm   138 ISMEGTELRDKVNIPVLMISHACKEEIAKKFSDTAGYRLRVRIDPGY----YELFRYLIPFLVVI 198

plant   176 SAVLASYF-------SVRRHRIRQHVRDLHHGGQGHSRMPKDLLQSMPTEVYTGVLEEGSTSVTC 233
            ....|.:.       .|.|.::.:.            |:.|..|:.:|.:.|    ..|....||
Worm   199 VFCFALFLITLCVRGCVERRKLNKR------------RLSKRNLKKIPVKKY----RLGDDPDTC 247

plant   234 AICIDDYRVGEILRILPCKHKYHAVCIDSWLGRCRSFCPVCKQNPRTGNDVPPASETTPLISPGP 298
            |||::.:..||.||.|||:|.:|..|||.||.:.|..||:||:...|.:|...::......|.||
Worm   248 AICLESFASGEKLRHLPCRHVFHCNCIDVWLTQTRKICPLCKRKIGTDSDSECSTNDLASTSQGP 312

plant   299 NSITSL------QSFYDLPI 312
            |..|:|      ||.::||:
Worm   313 NDATALYNNADNQSGFELPV 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AT1G35625	NP_001319153.1	None
C18B12.4	NP_510498.1	PA	<74..176	CDD:333703	21/102 (21%)
		HRD1	<223..>335	CDD:227568	42/126 (33%)
		RING-H2_RNF103	246..291	CDD:319387	24/44 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2961
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	81	1.000	Inparanoid score	I2122
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	1	1.000	-	-		otm278
orthoMCL	1	0.900	-	-		OOG6_103040
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.760