Protein Alignment SPARCL1 and Fs

DIOPT Version :9

• Sequence 1: NP_001121782.1
• Gene: SPARCL1 / 8404
• HGNCID: 11220
• Length: 664
• Species: Homo sapiens
• Sequence 2: NP_652376.2
• Gene: Fs / 2768836
• FlyBaseID: FBgn0259878
• Length: 767
• Species: Drosophila melanogaster
• Alignment Length: 494
• Identity: 110/494 - (22%)
• Similarity: 170/494 - (34%)
• Gaps: 156/494 - (31%)

Human    84 SAEQGKSSSQELGLKDQEDSDGHLSVNLEYAPTEGTLDIKEDMSEPQEKK--LSENTDFLAPGVS 146
            :|.:.::..|||.|:.:.:.:                :.:::|..|:|.:  .||||:|     :
  Fly   303 AALRRRTHQQELELEQEPELE----------------EEQQEMKPPRESRSLSSENTNF-----N 346

Human   147 SFTDSNQQESITKREENQE--QPRNYSHHQL---NRSSKHSQGLRDQGNQEQDPNISNGEEEEEK 206
            ...|..|::    |.:||.  |||...|.:|   :.||:.|..|.||....:...:.....|..:
  Fly   347 LGLDGGQRQ----RADNQRKLQPRESKHRRLLIIDSSSRSSSNLPDQPTSGRRGRVEMTGYERRR 407

Human   207 EPGEVGTH---------NDN------------------QERKTELPREHANSKQEEDNTQSDD-- 242
            .....|.|         ||:                  |.|...|  .:||....:.|.||..
  Fly   408 HRNNHGKHLTRSMTTGANDSFPADKTPAQSPAADSILAQSRLANL--ANANEPANDINRQSSTRV 470

Human   243 ------ILEESDQPTQ-VSKMQEDEFDQGNQEQEDNSNAEMEEENASNVNKHIQETEWQSQEGKT 300
                  .:|.:..|.. :.|.|..:..|...:.:|..|.|.:..|.         |...|..|.|
  Fly   471 RHQHARRIEHAPNPDNGLRKRQHKQQQQHQHQHQDRMNTEAQSANT---------TVSGSGSGAT 526

Human   301 GLEAISNHKETEEKTVSEALLMEPTDDGNTTPRNHGVDDDGDDDGDDGGTDGPRHSASDDYFIPS 365
            ....||..:...|...|       :|..||....|           .||...|         :|.
  Fly   527 NHRRISQLQHGSETAAS-------SDLANTHDLAH-----------LGGIYAP---------LPP 564

Human   366 QAFLEAERAQSIAYHLKIEEQREKVHENENIGT---TEPGEHQEAKKAENSSNEE-ETSSEGNMR 426
            |                        |.|...||   |...|.|..|:|..::|.: |.:..|
  Fly   565 Q------------------------HSNPVCGTDGRTYNTECQLRKRACRTNNAQLEVAYRG--- 602

Human   427 VHAVDSCMSFQCKRGHICKADQQGKPHCV-CQDPVTCP------PTKPLDQ---VCGTDNQTYAS 481
             |..:||....|..|..|..||...|||: |:  :.||      .:...|:   |||.|.:||.|
  Fly   603 -HCKNSCSGVHCLNGLTCVEDQYLMPHCIACR--IECPWDNLDVDSSGYDERQAVCGVDGKTYRS 664

Human   482 SCHLFATKCRLEGTKKGHQLQLDYFGACKS-IPTCTDFE 519
            :|.:....|::     |..:.:.|.|.|:: ..:|.|.:
  Fly   665 ACDINRMICKI-----GRSIAVAYPGPCRAGRVSCADIK 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPARCL1	NP_001121782.1	O-glycosylated at one additional site	25..34
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	28..360		66/318 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	388..426		12/41 (29%)
		KAZAL_FS	433..512	CDD:294071	26/89 (29%)
		SPARC_Ca_bdg	513..648	CDD:287550	2/7 (29%)
		SPARC_EC	514..662	CDD:238155	2/6 (33%)
Fs	NP_652376.2	KAZAL	564..604	CDD:197624	13/67 (19%)
		KAZAL_FS	654..687	CDD:238052	12/37 (32%)
		KAZAL_FS	723..767	CDD:238052

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4004
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900