Protein Alignment CASP7 and Drice

DIOPT Version :9

• Sequence 1: NP_001253986.1
• Gene: CASP7 / 840
• HGNCID: 1508
• Length: 388
• Species: Homo sapiens
• Sequence 2: NP_524551.2
• Gene: Drice / 43514
• FlyBaseID: FBgn0019972
• Length: 339
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 118/272 - (43%)
• Similarity: 167/272 - (61%)
• Gaps: 14/272 - (5%)

Human   121 TSKKKKNVTMRSIKTTRDRVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKC 185
            :|..:|||.    |...|| ...:|||..:..|..:|.|:::|: |..:..|.||:.|.|.|.:.
  Fly    67 SSSYRKNVA----KMVTDR-HAAEYNMRHKNRGMALIFNHEHFE-VPTLKSRAGTNVDCENLTRV 125

Human   186 FRSLGFDVIVYNDCSCAKMQDLLKK---ASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDL 247
            .:.|.|:|.||.||   :.:|:|:.   |:.::|:::.|....:|||||...||.||....:.::
  Fly   126 LKQLDFEVTVYKDC---RYKDILRTIEYAASQNHSDSDCILVAILSHGEMGYIYAKDTQYKLDNI 187

Human   248 TAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQAD-SGPINDTDANPRYKIPVEADFLFAYSTV 311
            .:.|..:.|.:|..||||||||||:|..||.|:... |....|.|::..|||||.||||.|||||
  Fly   188 WSFFTANHCPSLAGKPKLFFIQACQGDRLDGGVTMQRSQTETDGDSSMSYKIPVHADFLIAYSTV 252

Human   312 PGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFES-QSDDPHFHEKKQIPC 375
            ||:||||:..|||||:|:||:.|..:||.|:|:.:||.|..|||..||| ..|.|..|::|||||
  Fly   253 PGFYSWRNTTRGSWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPC 317

Human   376 VVSMLTKELYFS 387
            :.:|||:.|.||
  Fly   318 ITTMLTRILRFS 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CASP7	NP_001253986.1	CASc	145..386	CDD:237997	109/245 (44%)
Drice	NP_524551.2	CASc	86..330	CDD:214521	111/248 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147028
Domainoid	1	1.000	199	1.000	Domainoid score	I3057
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11168
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3668
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	1	1.000	-	-		mtm8526
orthoMCL	1	0.900	-	-		OOG6_103710
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3066
SonicParanoid	1	1.000	-	-		X460
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.690