Protein Alignment SPNS1 and Spns1

DIOPT Version :10

• Sequence 1: XP_047290695.1
• Gene: SPNS1 / 83985
• HGNCID: 30621
• Length: 586
• Species: Homo sapiens
• Sequence 2: NP_076201.2
• Gene: Spns1 / 73658
• MGIID: 1920908
• Length: 528
• Species: Mus musculus
• Alignment Length: 549
• Identity: 434/549 - (79%)
• Similarity: 446/549 - (81%)
• Gaps: 65/549 - (11%)

Human    46 MAGSDTAPFLSQADDPDDGPVPGTPGLPGSTGNPKSEEPEVPDQEGLQRITGLSPGRSALIVAVL 110
            ||||||||||||||||||||.||.|||||..|||||.|.||||.||||||||||.|.|.|||.||
Mouse     1 MAGSDTAPFLSQADDPDDGPAPGHPGLPGPMGNPKSGELEVPDCEGLQRITGLSRGHSTLIVVVL 65

Human   111 CYINLLNYMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFGYLGDRYNRKYLMCG 175
            ||||||||||||||||||.||||||||||.|:|||||||||||||||||||||||||||||||||
Mouse    66 CYINLLNYMDRFTVAGVLTDIEQFFNIGDGSTGLIQTVFISSYMVLAPVFGYLGDRYNRKYLMCG 130

Human   176 GIAFWSLVTLGSSFIPGEHFWLLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFYFAI 240
            ||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 GIAFWSLVTLGSSFIPREHFWLLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFYFAI 195

Human   241 PVGSGLGYIAGSKVKDMAGDWHWALRVTPGLGVVAVLLLFLVVREPPRGAVERHSDLPPLNPTSW 305
            ||||||||||||||||:||||||||||||||||:|||||||||:|||||||||||..|||:||||
Mouse   196 PVGSGLGYIAGSKVKDVAGDWHWALRVTPGLGVLAVLLLFLVVQEPPRGAVERHSGSPPLSPTSW 260

Human   306 WADLRALARNPSFVLSSLGFTAVAFVTGSLALWAPAFLLRSRVVLGETPPCLPGDSCSSSDSLIF 370
            ||||:||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||
Mouse   261 WADLKALARNPSFVLSSLGFTSVAFVTGSLALWAPAFLLRSRVVLGETPPCLPGDSCSSSDSLIF 325

Human   371 GLITCLTGVLGVGLGVEISRRLRHSNPRADPLVCATGLLGSAPFLFLSLACARGSIVATYIFIFI 435
            |||||||||||||||||||||||..||||||||||.|||||||||||:|||||||||||||||||
Mouse   326 GLITCLTGVLGVGLGVEISRRLRRFNPRADPLVCAAGLLGSAPFLFLALACARGSIVATYIFIFI 390

Human   436 GETLLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDAGSPYLIGLACCTKQGPQTTGLWC 500
            ||||||||||||||||||||||||||||||||||||||||||||||||||.
Mouse   391 GETLLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDAGSPYLIGLI-------------- 441

Human   501 PSGAAPPACPWPVCSSERLPLTYLHICHSWPWAHPTK---------------GLGLTPWPGPASR 550
                           |:||.       .|||.:..::               .||     |.|..
Mouse   442 ---------------SDRLR-------RSWPPSFLSEFRALQFSLMLCAFVGALG-----GAAFL 479

Human   551 GTL-----GRVPAPRHYLGLLKTVGHSSG 574
            ||.     .|..|..|..|||    |.||
Mouse   480 GTAMFIEDDRRRAQLHVQGLL----HESG 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPNS1	XP_047290695.1	MFS_spinster_like	107..499	CDD:340886	362/391 (93%)
Spns1	NP_076201.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		32/36 (89%)
		MFS_spinster_like	62..479	CDD:340886	372/457 (81%)