Protein Alignment SPNS1 and mfc1

DIOPT Version :10

• Sequence 1: XP_047290695.1
• Gene: SPNS1 / 83985
• HGNCID: 30621
• Length: 586
• Species: Homo sapiens
• Sequence 2: NP_001342985.1
• Gene: mfc1 / 3361480
• PomBaseID: SPAPB1A11.01
• Length: 495
• Species: Schizosaccharomyces pombe
• Alignment Length: 280
• Identity: 55/280 - (19%)
• Similarity: 111/280 - (39%)
• Gaps: 68/280 - (24%)

Human   115 LLNYMDRFTVAG------VLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFGYLGDRYNRKYLM 173
            ::::|....:.|      .:|::.:.|...::...|..|:::...|:...:|..|.:.|.|:.|.
pombe    44 IISFMTMLCMYGSSVFMPSIPELCEKFGEPETLVVLGATLYVIGVMLGPLIFSPLSELYGRRPLN 108

Human   174 CGGIAFWSLVTLGSSFIPGEHFWLLLLTR------GLVGVGEASYSTIAPTLIADLFVADQRSRM 232
            ..|...::|:.:.::.  ..:..:.::.|      |.||:|      |....::|:|....|.:.
pombe   109 IFGYTLFALMQIPTAL--SVNLAMFVVFRFFSGFFGSVGLG------IGAGSLSDMFSKRDRGKY 165

Human   233 LSIFYFAIPVGSGL-----GYIAGSKVKDMAGDWHWALRVTPGLGVVAVL--LLFL-------VV 283
            :.|::..|.:|..:     |:||||.:     .|.|...:...|..|::|  ::||       :.
pombe   166 IGIYFLGICLGPAIAPIASGFIAGSSI-----SWRWEFWILLMLSGVSLLAGVVFLKETYAPVLK 225

Human   284 REPPRGAVERHSD--------------LPPLNPTSWWAD------------LRALARNPSFVLSS 322
            |:..:..:|:..:              ...::|...:|:            |..|...|..:|.|
pombe   226 RKQAKKLLEKQENQKSVEVKISEITESSQQIDPDKSFAEVVHILVTTIRRPLHLLCTQPIMILIS 290

Human   323 LGFTAVAFVTGSLALWAPAF 342
            |   .|..|.|.|.|...||
pombe   291 L---IVGTVYGILYLLFTAF 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPNS1	XP_047290695.1	MFS_spinster_like	107..499	CDD:340886	55/280 (20%)
mfc1	NP_001342985.1	MFS_Tpo1_MDR_like	46..485	CDD:340881	55/278 (20%)