Protein Alignment SPNS1 and SPOM_SPAC11D3.18C

DIOPT Version :10

• Sequence 1: XP_047290695.1
• Gene: SPNS1 / 83985
• HGNCID: 30621
• Length: 586
• Species: Homo sapiens
• Sequence 2: NP_001342807.1
• Gene: SPOM_SPAC11D3.18C / 2543005
• PomBaseID: SPAC11D3.18C
• Length: 498
• Species: Schizosaccharomyces pombe
• Alignment Length: 466
• Identity: 83/466 - (17%)
• Similarity: 156/466 - (33%)
• Gaps: 181/466 - (38%)

Human   129 PDIEQFFNIGDSSSGLI-----QTVFISSYMVLAPVFGYL------------------------- 163
            ||::    .||::|..|     :.:.:...:|::|:.|:|
pombe    33 PDVD----YGDTASLKIDPKVEKKLLLKMDLVISPIIGFLYLMAFLDRSNIGNAAVAGMTEALSL 93

Human   164 -GDRYN------------------------RKYLMCGGIAF-WSLVTLGSSFIPGEHFWLLLLTR 202
             |:|.|                        :...|...|:| ||:..|.|.|:  ..:..|:.||
pombe    94 YGERLNVAVSIFYVLYILVETPSVVLVKRIKASRMLAFISFAWSMTVLFSGFM--SSYGGLIATR 156

Human   203 GLVGVGEASYSTIAPTLIADLFVA------DQRSRMLSIFYFAIPVGSGLGYIAGSKVKDMAGD- 260
            .::|:.|   ..:.|.|  :|::.      :|..|:..:|..|...|:..|..|.:..:..||:
pombe   157 LILGLLE---GCLFPAL--NLYLTTHYTRKEQCQRLSYLFASAGLAGAFGGLFAYALEQVHAGNK 216

Human   261 --WHWALRVTPGLGVVAV-LLLF----------LVVREPPRGAV-----------ERHSDLPPLN 301
              |.|...|...:..:.| |.||          .:.||....|:           |:|.:
pombe   217 EGWQWIYIVEGLVSFIGVPLCLFALPDKMENAWFLTREEREVAIIRRDINARYHGEQHFE----- 276

Human   302 PTSWWADLRALARNPSFVLSSLGFTAVAFVTGSLALWAPAFLLRSRVVLGETPPCLPGDSCSSSD 366
                |:::|...::|...:|:                                     .|...:|
pombe   277 ----WSEVRKAFKDPKVYVSA-------------------------------------TSQFCAD 300

Human   367 SLIFGLITCLTGVL-GVG-LGVEISRRLRHSNPRADPLVCATGLLGSAPFLFLSLACARGSIVAT 429
            .:::|..:.|..:: |:| :|::       :|....|:..|    |...|||::....|..:.|.
pombe   301 MVLYGFSSFLPVIIKGLGFVGLQ-------TNYMTIPVYIA----GVISFLFVAWLSDRTQLRAV 354

Human   430 YIFIFIGETLLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDAGSPYLIGLACCTKQGPQ 494
            |        |:|.:..:...   |:::....|.|..:.           :.|:|.:.|..  ||.
pombe   355 Y--------LISASTVVAVG---YIIMLASDSNAAKYT-----------ATYIIAIGCYI--GPG 395

Human   495 TTGLWCPSGAA 505
            ....|..:..|
pombe   396 LNLGWLNNNVA 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPNS1	XP_047290695.1	MFS_spinster_like	107..499	CDD:340886	81/458 (18%)
SPOM_SPAC11D3.18C	NP_001342807.1	MFS_FEN2_like	56..460	CDD:340885	77/439 (18%)