Protein Alignment SPNS1 and SPOM_SPBPB10D8.01

DIOPT Version :10

• Sequence 1: XP_047290695.1
• Gene: SPNS1 / 83985
• HGNCID: 30621
• Length: 586
• Species: Homo sapiens
• Sequence 2: NP_595045.1
• Gene: SPOM_SPBPB10D8.01 / 2541399
• PomBaseID: SPBPB10D8.01
• Length: 552
• Species: Schizosaccharomyces pombe
• Alignment Length: 556
• Identity: 102/556 - (18%)
• Similarity: 185/556 - (33%)
• Gaps: 170/556 - (30%)

Human    21 KCSGLLPRV-GSSVGPERGRARPPGTMAGSD-TAPFLSQADDPDDGPVPGTPGLPGSTGNPKSEE 83
            |..|..|.| .|.:.....::.|..:.|..| |..|:.:|                     |..|
pombe    28 KEKGYFPHVITSHISKSSSQSHPDVSNAVLDETFSFMQEA---------------------KDLE 71

Human    84 PEVPDQEGLQRITGLSPGRSAL---IVAVLCYINLLNYMDRFT-----VAGVLPDIEQFFNIGDS 140
            |..|.|:  :|:      |..|   ::.:|..::::.|:|:.|     :.|:..|.    :|..:
pombe    72 PLTPKQD--KRL------RWKLYFTVLVMLMILDMMLYIDKATLSYSSILGLFEDT----HINSN 124

Human   141 SSGLIQTVFISSYMVLAPVFGY-LGDRYNRKYLMCGGIAFWSLVTLGSSFI--PGEHFWLLLLTR 202
            ....|.|:|...: |:..:.|: |..|:.....:....|.|:::.    |:  ...:|..|:..|
pombe   125 QYNDINTLFYVGF-VIGQIPGHMLLQRFPVSKFVAASTALWTIII----FLHCAAYNFSGLMALR 184

Human   203 GLVGVGEASYSTIAPTLIA--DLFVADQRSRMLSIFYFAIPVGSGL--GYIA-GSK-VKDMAGDW 261
            ..:|:.|   |::.||:.|  .:|.......:|..|::....|..:  |:|| |.: .|:....|
pombe   185 FFLGLVE---SSLLPTMEATIGMFFPHSEQALLQPFFYISCYGCNIPAGFIAYGVQYAKNTISPW 246

Human   262 HWALRVTPGLGVVAVLLLFLV----------------------VREPPRGAVE-----RHSDLPP 299
            ...:.:..|:.....:.||..                      ||......:|     ::..:..
pombe   247 KLFMIIVGGITFFLTIGLFFYYPDNTSTARFLTKKERLYTVDRVRRSNHSGIESKTFKKYQVIEA 311

Human   300 L-NPTSWWADLRALARNPSFVLS---SLGFTAVAFVTGSLALWAPAFLLRSRVVLGETPPCLPGD 360
            | :|.:|...........|..|:   :|.||::
pombe   312 LKDPVTWLFTFHVFCNQLSNNLAYQQNLLFTSL-------------------------------- 344

Human   361 SCSSSDSLIFGLIT----CLTGVLGVGLGVEISRRLRHSNPRADPLVCATGLLGSAPFLFLSLAC 421
            :.|..:|.:.|:.:    |::.::...:...|..:....           |.:...|.:...:||
pombe   345 NVSDLNSTLVGVASAGYNCVSAIIATYMMSVIKNQSAFH-----------GAIWYIPSIAGGIAC 398

Human   422 AR-------GSIVATYIFIFIG-ETLLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDAG 478
            ..       |.:.|..|....| ..::|:.|. .|....|....||                  |
pombe   399 VAMSWDHKIGELAAIIIASNFGIPFIISLGWT-TASCAGYTKKLTR------------------G 444

Human   479 SPYLIGLACCTKQGPQTTGLWCPSGAAPPACP-WPV 513
            ..::||.|.....|||   :| .|..||...| |.|
pombe   445 VMFMIGYAIANIIGPQ---MW-QSRDAPRYYPAWIV 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPNS1	XP_047290695.1	MFS_spinster_like	107..499	CDD:340886	76/448 (17%)
SPOM_SPBPB10D8.01	NP_595045.1	MFS_FEN2_like	84..489	CDD:340885	84/471 (18%)