Protein Alignment SPNS1 and SPOM_SPBC1683.12

DIOPT Version :10

• Sequence 1: XP_047290695.1
• Gene: SPNS1 / 83985
• HGNCID: 30621
• Length: 586
• Species: Homo sapiens
• Sequence 2: NP_595068.1
• Gene: SPOM_SPBC1683.12 / 2539910
• PomBaseID: SPBC1683.12
• Length: 482
• Species: Schizosaccharomyces pombe
• Alignment Length: 455
• Identity: 93/455 - (20%)
• Similarity: 167/455 - (36%)
• Gaps: 123/455 - (27%)

Human   106 IVAVLCYINLLNYMDR-----FTVAGVLPDIE-QFFNIGDSSSGLIQTVFISSYMVLAPVFGYLG 164
            ::.:...:..|:::||     ..|.|:..|:: |.:....:.|     ||.::|:........|.
pombe    44 LMPMFSVLYFLSFLDRANIGNAAVVGLKEDLKLQAYQYSAAVS-----VFYATYITAETPSVLLV 103

Human   165 DRYNRKYLMCGGIAFWSLVTLGSSFIPGEHFWLLLLTRGLVGVGEASYSTIAPTLIADLFVADQR 229
            .::...|.:...|..|||||:.:.|:  .|:|.|:|||.|:|:.|..:.......|:..:..:::
pombe   104 KKFGPHYYLSAMIIGWSLVTIFTCFV--RHYWSLVLTRLLLGICEGGFFPCLSLYISMTYKREEQ 166

Human   230 SRMLSIFY--------FAIPVGSGLGYIAGSKVKDMAG--DWHWALRVTPGL--GVVAVLLLFLV 282
            .:.|:..|        |...:.:||     :|:...:|  :|.| |.:..||  .:.|:.:||.:
pombe   167 GKRLAYLYVCSCFSGAFGGLIATGL-----TKIPKSSGLPNWGW-LYIIEGLISAISALWILFCL 225

Human   283 VREP--PRGAVERHSDLPPL----------NPTSWWADLRALARNPSFVLSSLGFTAVAFVTGSL 335
            ..:|  .|....|..:|..:          :|...|...|...::|...:|.:    :.|
pombe   226 PDDPSTARFLNPREKELMKIRAEQRQKYMGSPNFDWTQFRKAFKDPKMYMSCV----IQF----- 281

Human   336 ALWAPAFLLRSRVVLGETPPCLPGDSCSSSDSLIFGLITCLTGVLGVGLGVEISRRLRHSNPRAD 400
                                      |  .|.:::|:.|.|..:|.:.||        :|:..|.
pombe   282 --------------------------C--QDLVLYGISTFLPSILKLELG--------YSSLAAQ 310

Human   401 PLVCATGLLGSAPFLFLSLACARGSIVATYI----------FIFIGETLLSMNWAIVADILLYVV 455
            .:......||......:.|...|.:|...:|          ||.:..|..|....:...::...:
pombe   311 YMSVPVYALGGISVYVICLLSDRTNIRGWFIIGMNFFGLAGFIILLATTNSAANYVATYLIALPL 375

Human   456 IPT----------------RRSTAEAFQIVLSHLLG-DAG-----SPYLIG---LACCTKQGPQT 495
            .||                ||:||......:.:|.| .||     |||.:|   ...||..|..|
pombe   376 YPTVALNITWINNNMAPHYRRATALGCNQTIGNLAGVIAGQVYRSSPYKLGHGFALGCTVVGTLT 440

Human   496  495
            pombe   441  440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPNS1	XP_047290695.1	MFS_spinster_like	107..499	CDD:340886	93/454 (20%)
SPOM_SPBC1683.12	NP_595068.1	MFS_FEN2_like	39..441	CDD:340885	93/455 (20%)