Protein Alignment SPNS1 and spin-2

DIOPT Version :10

• Sequence 1: XP_047290695.1
• Gene: SPNS1 / 83985
• HGNCID: 30621
• Length: 586
• Species: Homo sapiens
• Sequence 2: NP_502513.1
• Gene: spin-2 / 178256
• WormBaseID: WBGene00008033
• Length: 488
• Species: Caenorhabditis elegans
• Alignment Length: 398
• Identity: 176/398 - (44%)
• Similarity: 241/398 - (60%)
• Gaps: 25/398 - (6%)

Human   107 VAVLCYINLLNYMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFGYLGDRYNRKY 171
            |..|..:|||||:||:||||||..::.::||.||..|||||||:.|:||.:||.||||||:|||:
 Worm    11 VTALFVVNLLNYVDRYTVAGVLTQVQTYYNISDSLGGLIQTVFLISFMVFSPVCGYLGDRFNRKW 75

Human   172 LMCGGIAFWSLVTLGSSFIPGEHFWLLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIF 236
            :|..|:..|....|||||:|..||||.|:.|..||:||||||.:||:||:|:|...:||.:..||
 Worm    76 IMIIGVGIWLGAVLGSSFVPANHFWLFLVLRSFVGIGEASYSNVAPSLISDMFNGQKRSTVFMIF 140

Human   237 YFAIPVGSGLGYIAGSKVKDMAGDWHWALRVTPGLGVVAVLLLFLVVREPPRGAVER----HSDL 297
            |||||||||||:|.||.|..:.|.|.|.:||:...|::.::.|.|...||.|||.::    ..|:
 Worm   141 YFAIPVGSGLGFIVGSNVATLTGHWQWGIRVSAIAGLIVMIALVLFTYEPERGAADKAMGESKDV 205

Human   298 PPLNPTSWWADLRALARNPSFVLSSLGFTAVAFVTGSLALWAPA---FLLRSRVVLGETPPCLPG 359
            .....|::..||..|.:.|:.|..:.|:||:.||:|:|:.|.|.   .|......|.:|
 Worm   206 VVTTNTTYLEDLVILLKTPTLVACTWGYTALVFVSGTLSWWEPTVIQHLTAWHQGLNDT------ 264

Human   360 DSCSSSD----SLIFGLITCLTGVLGVGLGVEISRRL--------RHSNPRADPLVCATGLLGSA 412
            ...:|:|    :|.||.||...|::||..|..:|:.|        |....||.|||...|.|.:|
 Worm   265 KDLASTDKDRVALYFGAITTAGGLIGVIFGSMLSKWLVAGWGPFRRLQTDRAQPLVAGGGALLAA 329

Human   413 PFLFLSLACARGSIVATYIFIFIGETLLSMNWAIVADILLYVVIPTRRSTAEAFQIVLSHLLGDA 477
            |||.:.:.....|:|..||.||.|.|.:..||.:..|:|..|:.|.|||||.::.:::|||.|||
 Worm   330 PFLLIGMIFGDKSLVLLYIMIFFGITFMCFNWGLNIDMLTTVIHPNRRSTAFSYFVLVSHLFGDA 394

Human   478 GSPYLIGL 485
            ..||||||
 Worm   395 SGPYLIGL 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPNS1	XP_047290695.1	MFS_spinster_like	107..499	CDD:340886	176/398 (44%)
spin-2	NP_502513.1	MFS_spinster_like	11..440	CDD:340886	176/398 (44%)