Protein Alignment TSSK6 and grp

DIOPT Version :10

• Sequence 1: NP_114426.1
• Gene: TSSK6 / 83983
• HGNCID: 30410
• Length: 273
• Species: Homo sapiens
• Sequence 2: NP_477011.1
• Gene: grp / 34993
• FlyBaseID: FBgn0261278
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 279
• Identity: 84/279 - (30%)
• Similarity: 135/279 - (48%)
• Gaps: 44/279 - (15%)

Human    11 GYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHV 75
            |:.|.:|:|||:|.:||:..:::....||:|:||.:: .||..|. :.:|:.|.:.::..||:..
  Fly    21 GWTLAQTLGEGAYGEVKLLINRQTGEAVAMKMVDLKK-HPDAANS-VRKEVCIQKMLQDKHILRF 83

Human    76 FEFIEVCNGKL------YIVME-AAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVH 133
            |       ||.      ||.:| ||..:|...::.:..:|..:|:..|.|:...:.|||...:.|
  Fly    84 F-------GKRSQGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAH 141

Human   134 RDLKCENVLLSPDER-RVKLTDFGFGR--QAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDV 195
            ||||.||:||  ||. .||::|||...  :..|...|....||:..|.:||||.. .|..:..|:
  Fly   142 RDLKPENLLL--DEHDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVLQK-AYHAQPADL 203

Human   196 WSMGVVLYVMVTGCMPFD-------------DSDIAGLPRRQKRGVLYPEGLELSERCKALIAEL 247
            ||.||:|..|:.|.:|:|             |:|         ...|.....:|.....:|:.:|
  Fly   204 WSCGVILVTMLAGELPWDQPSTNCTEFTNWRDND---------HWQLQTPWSKLDTLAISLLRKL 259

Human   248 LQFSPSARPSAGQVARNCW 266
            |..||..|.:..:...:.|
  Fly   260 LATSPGTRLTLEKTLDHKW 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSSK6	NP_114426.1	STKc_TSSK6-like	11..267	CDD:271066	84/279 (30%)
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	84/279 (30%)