Protein Alignment PIP5K1B and PIP5K59B

DIOPT Version :10

• Sequence 1: NP_003549.1
• Gene: PIP5K1B / 8395
• HGNCID: 8995
• Length: 540
• Species: Homo sapiens
• Sequence 2: NP_001369113.1
• Gene: PIP5K59B / 37633
• FlyBaseID: FBgn0034789
• Length: 891
• Species: Drosophila melanogaster
• Alignment Length: 497
• Identity: 271/497 - (54%)
• Similarity: 342/497 - (68%)
• Gaps: 66/497 - (13%)

Human    18 EKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFR 82
            |.||||..:|.|.|:|||||.:|||:|.|||:||:||.||:.:||:..|.|||:|||||||.:||
  Fly    69 EITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFR 133

Human    83 FKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEF 147
            :|.|||:||||||:||||:|||::.|:|:.||.||||||||||:|::|:|||||||||||||.||
  Fly   134 YKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEF 198

Human   148 LQKLLPGYYMNLNQNPRTLLPKFYGLYCMQ-SGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKR 211
            |||||||||||||||||||||||:||||:| |...|||:|||||:||.|::||..|||||||:||
  Fly   199 LQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKR 263

Human   212 RASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFL 276
            :|::.||.|.:||:|||||::....|::.:.|||.||:||:||||.|||||||||||||||:|.|
  Fly   264 KANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNL 328

Human   277 DHSLKEK--EEETPQNVPDAK--------------RTGMQK---------VLYSTAMESIQGPGK 316
            |.:||||  |:..|...|.|:              .||:.:         |.:||||||||.
  Fly   329 DVALKEKQSEQRKPLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAHSTAMESIQA--- 390

Human   317 SGDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSVHRPS 381
            ..:.|..|.....|||||:|.:||:|||::|||||||||||.|||||::|::::||:||||.|||
  Fly   391 ESEPIDDEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPS 455

Human   382 FYADRFLKFMNSRVFKKIQ----------------------ALKASPSKKRCNSIAALKATSQEI 424
            |||.||..||...||:||.                      |||.||||:        |:.|:.|
  Fly   456 FYAQRFQNFMAKTVFRKIPSLDLPEIKGNHRKFRTLVTSYIALKHSPSKR--------KSLSKAI 512

Human   425 VSSISQEWKDEKRDLLTEGQSFSSLDEEALGSRHRPDLVPST 466
            ..||..:.:...|. :....|.||      |..|:|...|:|
  Fly   513 QRSIDSDNEVASRP-VHASHSHSS------GKIHQPAKPPTT 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K1B	NP_003549.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		1/2 (50%)
		PIPKc_PIP5K1B	27..400	CDD:340444	244/398 (61%)
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	243/397 (61%)