Protein Alignment TSSK1B and KP78b

DIOPT Version :10

• Sequence 1: NP_114417.1
• Gene: TSSK1B / 83942
• HGNCID: 14968
• Length: 367
• Species: Homo sapiens
• Sequence 2: NP_650065.1
• Gene: KP78b / 41361
• FlyBaseID: FBgn0026063
• Length: 604
• Species: Drosophila melanogaster
• Alignment Length: 377
• Identity: 121/377 - (32%)
• Similarity: 176/377 - (46%)
• Gaps: 72/377 - (19%)

Human    18 LGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFETS 82
            ||:|::||||.|........||||:|| |.|......:.|.||:.|:..|||.:|::..::.| |
  Fly    69 LGKGNFAKVKLAIHLPTGREVAIKLID-KTALNTIARQKLYREVNIMKKLNHPNIVRLLQVIE-S 131

Human    83 HGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKD 147
            ...:|:|||....|:|...:...|.:.|.:||..|.||..||:|||...:||||||.:|||||:.
  Fly   132 ERTLYLVMEYVSGGELFNYLVKNGRMRERDARVLFRQLVSAIEYCHSKSIVHRDLKAENLLLDQQ 196

Human   148 FNIKLSDFSFS-----KRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILY 207
            ..:|::||.||     |..|          :||||||.|||||:.:|..|.....|.|||||:||
  Fly   197 MKLKIADFGFSTTFEPKAPL----------ETFCGSPPYAAPELFRGKKYSGPEVDSWSLGVVLY 251

Human   208 IMVCGSMPYDDSNIKKMLR---IQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSH 269
            .:|.||:|:|.:|:|: ||   ::.::||.:    :::.||:.||...|..:..:|..:..:::.
  Fly   252 TLVSGSLPFDGTNLKE-LRDRVLRGKYRVPY----YVSIECESLIRKFLVLNPTQRTSLSAVMAD 311

Human   270 CWMQPKARGSPSVAINKEGESSRGTEPLWTPEPGSDKKSATKL--------EPEGEAQPQAQPE- 325
            .|            ||...|...|..|.  .|...|.....:|        :|....|.....:
  Fly   312 RW------------INMGYEQGNGLRPF--QEKPMDLHDVNRLSLLSNMGHKPRDVEQSLKNQKF 362

Human   326 ------------TKPEGTAMQMSRQSEILGFPSKPSTMETEEGPPQQPPETR 365
                        .||..||.            |:.|.....|.|...|..:|
  Fly   363 DDIYCTYMLLDVAKPRSTAC------------SEKSGSSFRETPTAMPGSSR 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TSSK1B	NP_114417.1	STKc_TSSK1_2-like	10..272	CDD:271067	100/261 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..367		20/111 (18%)
KP78b	NP_650065.1	Protein Kinases, catalytic domain	63..314	CDD:473864	101/273 (37%)
		UBA_MARK_Par1	335..373	CDD:270522	3/37 (8%)