Protein Alignment CASP6 and Decay

DIOPT Version :9

• Sequence 1: NP_001217.2
• Gene: CASP6 / 839
• HGNCID: 1507
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_477462.1
• Gene: Decay / 42008
• FlyBaseID: FBgn0028381
• Length: 308
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 91/263 - (34%)
• Similarity: 133/263 - (50%)
• Gaps: 21/263 - (7%)

Human    43 RRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVS 107
            |.|||||.||:.....   .:|.||..|||::.......||:|:.|:||...|:...:.||:...
  Fly    54 RAGIALILNHKDVKGQ---KQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLKEVARED 115

Human   108 HADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPV 172
            |:..||||...:|||....:||.|....::.|...|.||.|.:|..|||:|.||||||..
  Fly   116 HSQNDCFVLAVMSHGTEGKVYAKDMSYPVERLWNPFLGDNCKTLKNKPKLFFIQACRGAN----- 175

Human   173 IPLDVVDNQTEKLDTNITEVDAASV----YTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLC 233
            :...|..:....:...:....||:|    |.:|:.||.|:.||..:.::|.|...:|||:||.||
  Fly   176 LEKAVEFSSFAVMTRELVPEPAAAVQPITYAIPSTADILVFYSTFDKFFSFRNVDDGSWFIQSLC 240

Human   234 EMLGKYGSS-------LEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCFASMLTK--KLHFF 289
            .:|.:..::       :|...|||.|||||:.......|:.:....|::|.|.|.|||  :|...
  Fly   241 RVLDQAAANEAATPEGVELLRLLTAVNRKVAYEYQSNTKNEALNQMKEMPNFMSTLTKTFQLRVK 305

Human   290 PKS 292
            ||:
  Fly   306 PKT 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CASP6	NP_001217.2	CASc	37..290	CDD:214521	89/259 (34%)
Decay	NP_477462.1	CASc	54..302	CDD:237997	88/255 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152729
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850