Protein Alignment SLC25A2 and MME1

DIOPT Version :10

• Sequence 1: NP_114153.1
• Gene: SLC25A2 / 83884
• HGNCID: 22921
• Length: 301
• Species: Homo sapiens
• Sequence 2: NP_609093.1
• Gene: MME1 / 33987
• FlyBaseID: FBgn0031881
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 303
• Identity: 92/303 - (30%)
• Similarity: 147/303 - (48%)
• Gaps: 26/303 - (8%)

Human     2 KSGPGIQAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTF-------PDLYKGLTDCFLKTYAQVG 59
            ||.| :::.|   ||..||...||.|.|.|||||::||.       |..|||:.||..:|:...|
  Fly    11 KSNP-VKSFI---AGGVGGMCNVLVGHPLDTIKVRLQTMPTPPPGQPPRYKGVIDCAARTFRYEG 71

Human    60 LRGFYKGTGPALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALAL 124
            .||||:|....|:......:|.|..|...::..:    .|...:|:..|..|||:.|...:||..
  Fly    72 FRGFYRGISAPLVGVTPIYAVDFAVYAAGKRLFQ----TDDHIRLTYPQIFAAGALAGVCSALVT 132

Human   125 CPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVP-GYFFFF 188
            .||:.:|..|||   ..:|......:.||.:..| :.::.|....:.|..:.:|::.| |::|..
  Fly   133 VPTDRIKVLLQT---QTVSNGPLLYNGTIDTAAK-LYRQGGIRSLFKGTCACILRDSPTGFYFVT 193

Human   189 GGY--ELSRSFFASGRSKDELGPVHLMLSGGVAGICLWLVVFPVDCIKSRIQVLSMYGKQAGFIG 251
            ..:  ||:|...|:|:    :.....:||||.|||..|.:..|.|.:|||:|.......:.|...
  Fly   194 YEFLQELARKKSANGK----ISTTSTILSGGTAGIVFWTLAVPFDVLKSRLQSAPEGTYKHGIRS 254

Human   252 TLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYEYSRKMM 294
            ...:::..||..||:.|:...::||.|:..|:|...|.:..::
  Fly   255 VFRNLMATEGPKALFRGILPILLRAFPSTAAVFFGVELTNDLL 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A2	NP_114153.1	Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	7..91		33/90 (37%)
		Mito_carr	9..94	CDD:395101	33/91 (36%)
		Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	104..197		27/95 (28%)
		Mito_carr	<125..198	CDD:395101	19/75 (25%)
		Mito_carr	205..296	CDD:395101	26/90 (29%)
		Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	207..293		26/85 (31%)
MME1	NP_609093.1	Mito_carr	10..107	CDD:395101	36/103 (35%)
		Mito_carr	111..205	CDD:395101	27/97 (28%)
		Mito_carr	208..297	CDD:395101	27/92 (29%)