Protein Alignment TM2D2 and amx

DIOPT Version :10

• Sequence 1: NP_510882.1
• Gene: TM2D2 / 83877
• HGNCID: 24127
• Length: 214
• Species: Homo sapiens
• Sequence 2: NP_524644.1
• Gene: amx / 43869
• FlyBaseID: FBgn0000077
• Length: 284
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 61/263 - (23%)
• Similarity: 92/263 - (34%)
• Gaps: 93/263 - (35%)

Human    22 GNLLLLHCVSRSHSQNATAE-------------PELTSAGAAQPEGPGG-------------AAS 60
            ||.:.|......|..|:.|.             |.|.|:..|:..|..|             ::|
  Fly    36 GNQMDLSDSKGDHKDNSNASNGNGNANDNEVYVPPLVSSMVAKSGGGAGGLLDNITAYSSSSSSS 100

Human    61 WEYGDPHSPVILCSYLPDEFIECEDPVDHVGNATASQELGYGCLKFGGQAYSDVEHTSVQCHALD 125
            ...|:.:   :||.|      :.|.|.|.:..........:||: :|       ...:|.|..::
  Fly   101 SSNGNNN---MLCPY------DKETPCDRLQFPCIRCNYNHGCI-YG-------RDLNVTCEVIN 148

Human   126 GIECASPRTFLRE--------------------------------------------------NK 140
            .::|...|:|.|:                                                  |.
  Fly   149 NVQCLGERSFQRQMNCRYCYQTEMWQQSCGQRSSCNSATDKLFRTNCTVHHDVLCLGNRSFTRNL 213

Human   141 PCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLGIWWFVDLILLITGGLMPS 205
            .|....|:.:.|.||.|..||.||.|||.|||....:|||.:.||||:|..:|::|:....|.|:
  Fly   214 RCNWTQGYRWSTALLISLTLGGFGADRFYLGHWQEGIGKLFSFGGLGVWTIIDVLLISMHYLGPA 278

Human   206 DGS 208
            |||
  Fly   279 DGS 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM2D2	NP_510882.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..59		7/44 (16%)
		TM2	146..195	CDD:428337	24/48 (50%)
amx	NP_524644.1	TM2	219..268	CDD:428337	24/48 (50%)