DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment HMCN1 and him-4

DIOPT Version :9

Sequence 1:	NP_114141.2	Gene:	HMCN1 / 83872	HGNCID:	19194	Length:	5635	Species:	Homo sapiens
Sequence 2:	NP_001024582.1	Gene:	him-4 / 181187	WormBaseID:	WBGene00001863	Length:	5198	Species:	Caenorhabditis elegans

Alignment Length:	5987	Identity:	1661/5987 - (27%)
Similarity:	2518/5987 - (42%)	Gaps:	1163/5987 - (19%)

- Green bases have known domain annotations that are detailed below.

Human    10 VFLFALLYSSLAQDASPQSEIRAEEIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRP 74
            :.|.|...||:..|.:.         |.|.|:||||||:||||:||||||.|||:||.:|.:.:.
Worm    14 LLLLATTCSSVNDDKND---------PTGKSSLAFVFDITGSMFDDLVQVREGAAKIFKTVMAQR 69

Human    75 KRPLFNFALVPFHDPEIGPVTITTDPKKFQYELRELYVQGGGDCPEMSIGAIKIALEISLPGSFI 139
            ::.::|:.:||||||.:|.:..|||...|..:|.::||.|||||||.::..|..||:||||.|||
Worm    70 EKLIYNYIMVPFHDPYLGEIINTTDSTYFMRQLSKVYVHGGGDCPEKTLTGILKALQISLPSSFI 134

Human   140 YVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRTHIGYKVYEEIASTSSGQVFHLDKKQ 204
            |||||||||||.|..|||..||:|||.||||:||||.:|||.|::.||:||:.|.||||||:|..
Worm   135 YVFTDARSKDYHLEDEVLNTIQEKQSSVVFVMTGDCGNRTHPGFRTYEKIAAASFGQVFHLEKSD 199

Human   205 VNEVLKWVEEAVQASKVHLLSTDHLEQAVNTWRIPFDPSLKEVTVSLSGPSP-----MIEIRNPL 264
            |:.||::|..||:..||||:..........:..||.|..|.|:|:||||...     .|.:|:|.
Worm   200 VSTVLEYVRHAVKQKKVHLMYEARERGGTVSRNIPVDKHLSELTISLSGDKDDSDNLDIVLRDPE 264

Human   265 GKLIKKGF-----GLHELLNIHNSAKVVNVKEPEAGMWTVKTSSSGRHSVRITGLSTIDFRAGFS 324
            |:.:.|..     |..:|.|:    |::.:|:|..|:|||.|:|..:|::|:.|...:||:.||:
Worm   265 GRTVDKRLYSKEGGTIDLKNV----KLIRLKDPSPGVWTVNTNSRLKHTIRVFGHGAVDFKYGFA 325

Human   325 RKPTLDFKKTVSRPVQGIPTYVLLNTSGISTPARIDLLELLSISGSSL-KTIPVKYYPHRKPYGI 388
            .:|....:....|||....||:|:|.:|:..|..:..::|:...|.|| |.:.   .|||....:
Worm   326 SRPLDRIELARPRPVLNQDTYLLINMTGLIPPGTVGEIDLVDYHGHSLYKAVA---SPHRTNPNM 387

Human   389 WNISDFVPPNEAFFLKVTGYDKDDYLFQRVSSVSFSSIVPDAPKVTMPEKTPGYYLQPGQIPCSV 453
            :....||||...||::|.|||:|:|.|.|::..:..|::...|:..|......:..:...:.|:|
Worm   388 YFAGPFVPPKGLFFVRVQGYDEDNYEFMRIAPTAIGSVIVGGPRAFMSPIHQEFVGRDLNLSCTV 452

Human   454 DSLLPFTLSFVRNGVTL--GVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV 516
            :|...:|:.:|:.|..:  |...|.....|| ..|.:::|.|.|.|||..:|:.|....:|..:.
Worm   453 ESASAYTIYWVKTGEDIIGGPLFYHNTDTSV-WTIPELSLKDAGEYECRVISNNGNYSVKTRVET 516

Human   517 SEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSV 581
            .|.||.|....||:|..||.|.|.|...||.:..:.|.|....| ...|...|...|.:|::..|
Worm   517 RESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATV-FNGPNTERNPTNGTLKIHHV 580

Human   582 KFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWT 646
            ...|||.|.||..:.||.|...:.|.:.|||.|.|.|::..|.....|::.|.|.|.|||::.|.
Worm   581 TRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWY 645

Human   647 VNDMFIVGSHRYRMTSDGT-LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSE 710
            .....::..::|::..|.. |:|::|...|.|.|.|.|.:.||..:..:.|.....||:.::|::
Worm   646 FKGRHLLNDYKYQVGQDSKFLYIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNK 710

Human   711 LLVALGDITVMECKT-SGIPPPQVKWFKGDLEL-RPSTFLIIDPLLGLLKIQETQDLDAGDYTCV 773
            ::|..||....|||| .|.|.|:::|||...:| :|..::.|:.  |.|.|...:|.|||.|:||
Worm   711 MMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINE--GQLHIMGAKDEDAGAYSCV 773

Human   774 AINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD------NM 832
            ..|.||:......|.||..|..|:.|..|.:.|...|||.|...|.|.|.|:|::.:      |.
Worm   774 GENMAGKDVQVANLSVGRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLNN 838

Human   833 PIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPS 897
            |.:         :||..|.|.|.:....|:|.:.|.|.|.:|:....||:.|||||:|::|..|.
Worm   839 PRY---------TQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSPVLGHVPP 894

Human   898 VANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS-LHIERVQLQDGGEYTCV 961
            ...:||||.|||.|.::.|.|.|...|||:...:.:.|.|.:...|| |.:.....:|.|:|||:
Worm   895 EEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCI 959

Human   962 ASNVAGTNNKTTSVVVHVL----------------PTI-----QHGQQILST---IEGIPVTLPC 1002
            |.:.||  |.|..:.|.::                |||     :|...:.||   ::|....:||
Worm   960 AVSPAG--NSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIPC 1022

Human  1003 KASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLT 1067
            ..||.|.|.:.|...|..|:.:|..|:..||.:|.|.......||.|.|.|||:||..::|..:.
Worm  1023 VVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDNEQKTTIR 1087

Human  1068 VYVRPR---------------------VFGDQR----GLSQDKP--------------------- 1086
            :...|.                     |:||.:    .|..|||
Worm  1088 IMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLDDKPFTEGVVNEDGSLTIPNVNEAH 1152

Human  1087 ------------------VEISV---------------LAGEEVTLPCEVKSLPPPIITWAKETQ 1118
                              |.::|               |..:::.|.|..|:||||:..|..|.:
Worm  1153 RGTFTCHAQNAAGNDTRTVTLTVHTTPTINAENQEKIALQNDDIVLECPAKALPPPVRLWTYEGE 1217

Human  1119 LISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPK-IQRGPKHLKV 1182
            .|......||....|::.:...:..::|:::|..:|:||..:.:..|.||..|| |...|..:.|
Worm  1218 KIDSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDV 1282

Human  1183 QVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
            ..|..::|||.|.|.|..:.||:|.|..:.:|.:....:..|||.|.:|..:|.|.|.||.||.|
Worm  1283 VKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLRIYEADKNDIGNYNCVVTNEA 1347

Human  1248 GTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREP 1312
            ||.:....:.|||||.:    .|...|....|...|:|..|..:.:|..::.|...|..:.....
Worm  1348 GTSQMTTHVDVQEPPII----LPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTK 1408

Human  1313 GISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQL 1377
            |..:..||| |||.|.:..|...|.|.|.|.||..|....:.|...|.|||.:.||..|:..:..
Worm  1409 GYVVESDGT-LVIQSASVEDATIYTCKASNPAGKAEANLQVTVIASPDIKDPDVVTQESIKESHP 1472

Human  1378 TNLFCEVEGTPSPIIMWY-KDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQ 1441
            .:|:|.|...|.|.|.|| .|...:.:.::.:|.::.:.|.:|:|...|:|.|.|.|.|.||...
Worm  1473 FSLYCPVFSNPLPQISWYLNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGS 1537

Human  1442 KYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDG---KP---------- 1493
            |.|.::|:||..:..:.:..:|......:|.|.|.|.|.|.|.|:|..||   :|
Worm  1538 KSFQVEVIVPLNLDESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLS 1602

Human  1494 ---------------------------------------------------LFLG---------- 1497
                                                               :|||
Worm  1603 NDGLTLHFDSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQ 1667

Human  1498 --------------------DPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
                                ..||::...|..|::.:|:..:.|:|.|.|:|:|||..:.:.|.:
Worm  1668 TESDDKTTFVWSINGSESDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTLTLDV 1732

Human  1543 YIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPR 1607
            ..||.........:..::.|:.|.|:|:..|.|.|.:.|..||..:..|  .|:.:....|.|.:
Worm  1733 LEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGNDVDKS--WLFDESLSLLRIEK 1795

Human  1608 AQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMI--EGNLATPLNKQVVIAHSLTLECKAAGNPS 1670
            . ...||..:|...|.||||.:.|.:.....|..  ||:..|...:    :.::||:|
Worm  1796 L-TGKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRE----SETITLDC------- 1848

Human  1671 PI------LTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDV 1729
            |:      :||:|.|:|:..||.| ......:|.|::|.......|.|||.:.||:....::|.|
Worm  1849 PVSLGDFQITWMKQGLPLTENDAI-FTLDNTRLTILNANRDHEDIYTCVANNTAGQVSKDFDVVV 1912

Human  1730 LVPPAIEGGDETSYFIVMVNNLLE--LDCHVTGSPPPTIMW-LKDGQLIDERDGFKILLNGRKLV 1791
            .|.|.|:....|    :.:|...|  |.|...|:|.||..| ...|.|..|.   ..:.|...:|
Worm  1913 QVLPKIKNAVVT----LEINEGEEIILTCDAEGNPTPTAKWDFNQGDLPKEA---VFVNNNHTVV 1970

Human  1792 IAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGL--SERVVVKYKPVALQCIANGIP 1854
            :......:||:|:|.|.|..|...|...|.|...|..: |||  ||..|...:.:.|:|..:...
Worm  1971 VNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFE-SGLTESELTVNLTRSITLECDVDDAI 2034

Human  1855 NPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
            ...|:|..:.:|.......::..:.||.|.|.....:|.|.|.|..||.||...:...|.|..||
Worm  2035 GVGISWTVNGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPP 2099

Human  1920 SLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS 1984
            ::.:.|.  ..||:.:|.:.|.|:..|.|.||:||.||.|.:....|:..|:.||...|..|:|:
Worm  2100 TIVNEGG--EYTVIENNSLVLPCEVTGKPNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIA 2162

Human  1985 DAGIYKCVAINSAGATELFYSLQVHVAPSI-SGSNNMVAVVVNNPVRLEC------EARGIPAPS 2042
            ..|.|.|:|.|..|..|:.:.:.:...|.| .|..|:|..:....:..:|      ..:|    .
Worm  2163 HKGSYICMAKNDVGTAEISFDVDIITRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKG----Q 2223

Human  2043 LTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPN 2105
            :.||::..|:...:...::  ||..|.|.:.:...:|.|:|:|...|.|||...|....|.|||.
Worm  2224 IIWLRNYQPIDLEAEDARITRLSNDRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPT 2288

Human  2106 I--MGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKK------PGLSISENRSVLKIE 2162
            |  :.:::|.:.:....|.|.|.:...|.|.:||.|||..:..:      |...::.|:  |||.
Worm  2289 IIMLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQ--LKIT 2351

Human  2163 DAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIG----GSDELTQLTVIEGNLISLLCESSGI 2223
            ..:..|.|:|||||.|.||..|::.|||:...|.|.    .||..:|    :...:.:.|.....
Worm  2352 RIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQ----QNERVVISCPVYAR 2412

Human  2224 PPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYI 2288
            ||..:.|.|.|.|:.:|..  |:..:.|::|.:....::|::.|:|:|:|.|||.|:::.:.:.:
Worm  2413 PPAKITWLKAGKPLQSDKF--VKTSANGQKLYLFKLRETDSSKYTCIATNEAGTDKRDFKVSMLV 2475

Human  2289 RPTITNSGSHPT---EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQL 2350
            .|    |...|.   .|.|..|...:|.|..:|.|.||:||:|||:.:.........|.|..||:
Worm  2476 AP----SFDEPNIVRRITVNSGNPSTLHCPAKGSPSPTITWLKDGNAIEPNDRYVFFDAGRQLQI 2536

Human  2351 KNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPL 2415
            .....||.|||.|:|.|..|..|.:..|.|..||.|.|..|  |.::|:|..|..|.|:::...:
Worm  2537 SKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERR--EAVAVIEGFSSELFCDSNSTGV 2599

Human  2416 PSITWFKDGWPVSL-----SNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475
             .:.|.|||..::.     .:.::|.|.|:.:..:.....|:|:|||:|||.|||.||:|..:|.
Worm  2600 -DVEWQKDGLTINQDTLRGDSFIQIPSSGKKMSFLSARKSDSGRYTCIVRNPAGEARKLFDFAVN 2663

Human  2476 VPPHIVGENTLEDVK-VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE-AHHIISGGRFLQIT 2538
            .||.|..|.:..::: :.....|.:.|.|:|:|.|::.|..|.:||:.|. |:.:.:.|..|:|.
Worm  2664 DPPSISDELSSANIQTIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIV 2728

Human  2539 NVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEA-YSY 2602
            ..||.|.|.|||.|.:..|...:.|.:.|...|..     :...|:|...:.....|.|.| .|.
Worm  2729 RSQVEHAGTYTCEAQNNVGKARKDFLVRVTAPPHF-----EKEREEVVARVGDTMLLTCNAESSV 2788

Human  2603 PPATITWFKDGTPLESNRN----IRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE-VK 2662
            |.:::.|....   ||.:|    .:.....:||.:.|.|.|:.|.|.|.|.||||...|.:: :.
Worm  2789 PLSSVYWHAHD---ESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIV 2850

Human  2663 VYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANG 2727
            :..|..:::..|:         .|.:...|||:|.|...|..::.:.|||:.|...|.|:|.  |
Worm  2851 IETPYFLDQQKLY---------PIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--G 2904

Human  2728 HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIIN 2792
            .||.|...|....|||||:|.|.||..|.|..|.:.:||...|.|.  |:          :|...
Worm  2905 STLVIDNPQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWI--NV----------EVQAG 2957

Human  2793 NPISLYCETNAAPPPTLTWY----KDG----HPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCV 2849
            :|::|.|.........:||.    |||    ...:||||       ..|.|.:|..|||..|:|:
Worm  2958 DPLTLECPIEDTSGVHITWSRQFGKDGQLDMRAQSSSDK-------SKLYIMQATPEDADSYSCI 3015

Human  2850 AVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLL 2914
            |||:||.....:.|.|..||.|.|.:....|   ::.:.:..|.|.:.|.|.|..||..||:|:|
Worm  3016 AVNDAGGAEAVFQVTVNTPPKIFGDSFSTTE---IVADTTLEIPCRTEGIPPPEISWFLDGKPIL 3077

Human  2915 EDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVN 2979
            |.....:......|:|.|.:....|||.|||||.||.|::...:.:..||.|: ..||.:.||..
Worm  3078 EMPGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRVV-MASEVMRVVEG 3141

Human  2980 NFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT--LQIIRAKVSDGGEYTCIAINQAG 3042
            ...::.|||.|.|.|.::|||:.:|.   |:.|:....:.  |.:....::|||.|||||.|:||
Worm  3142 RQTTIRCEVFGNPEPVVNWLKDGEPY---TSDLLQFSTKLSYLHLRETTLADGGTYTCIATNKAG 3203

Human  3043 ESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107
            ||:....:.|.|||.|:|.:    .|:..:||.:..:.|:....|.|.:||.:||:.|.:...|
Worm  3204 ESQTTTDVEVLVPPRIEDEE----RVLQGKEGNTYMVHCQVTGRPVPYVTWKRNGKEIEQFNPV- 3263

Human  3108 ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREV-IVETISNPVTL 3171
                   |||:.|..:|.|:|.|.|.|.||....:|.::|:..|:.|..|... |||  .....:
Worm  3264 -------LHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNIVE--GESAKI 3319

Human  3172 TCDATGIPPPTIAWLKNHKRIENSDSLEVRILS-GGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235
            .|...|.|.|||:|||..:.. |.|::   ||| .|..|.|.::|..|.|.|||:|:|..|.:::
Worm  3320 ECKIDGHPKPTISWLKGGRPF-NMDNI---ILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQ 3380

Human  3236 YYFLSI-----------QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIAS 3289
            .:.:::           |.|.:|||.||            .|.|...|.|||.:.|.:....:.:
Worm  3381 DFKVNVYTKPYIDETIDQTPKAVAGGEI------------ILKCPVLGNPTPTVTWKRGDDAVPN 3433

Human  3290 GETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPT-IR--GNKDEAEK 3351
            .....|   .|...|.|....|.|.|:|:|:|.|.||.....:...|...|| :|  ||..|
Worm  3434 DSRHTI---VNNYDLKINSVTTEDAGQYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYE--- 3492

Human  3352 LMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVAS 3416
              .:.:.:|.::|..|..|.|.|:|.:...|:.|.....:...|..|.|.:|::||...|.|.||
Worm  3493 --VIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRAS 3555

Human  3417 NRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGL-DA 3480
            |.||..:....|::..||.:|.|........:...:..:.|...|.|.|.:.|.::|..:.: |:
Worm  3556 NEAGTSDIDLILKILVPPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDS 3620

Human  3481 HLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH--INGSE---EHEEISV 3540
            .:.::.:.....:...:..|.|:|||.|:|..|:.|..|.|.||.||.  |:|::   :.|..::
Worm  3621 RVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGDTI 3685

Human  3541 IVNNPLELTCIASGIPAPKM--TWMKDGRPL--PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLA 3601
            .:..|::|   |..|....|  :|.||.|.|  ..||.|.....|..|.||.|.:|:.|.|||:|
Worm  3686 TLTCPIKL---AEDIADQVMDVSWTKDSRALDGDLTDNVDISDDGRKLTISQASLENAGLYTCIA 3747

Human  3602 SSPAGDDDKEYLVRVHVPP--NIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQA 3664
            .:.||:...|:.|.:..||  :|:..|....:.|  |:...:.|.....|.|.|.||:||:.:..
Worm  3748 LNRAGEASLEFKVEILSPPVIDISRNDVQPQVAV--NQPTIMRCAVTGHPFPSIKWLKNGKEVTD 3810

Human  3665 TPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKS 3729
            ...:||:..|:.|||...|......::|||.|.||....|.:|.|..||.:.....:.:..|.::
Worm  3811 DENIRIVEQGQVLQILRTDSDHAGKWSCVAENDAGVKELEMVLDVFTPPVVSVKSDNPIKALGET 3875

Human  3730 TVLECIAEGVPTPRITWRKDGAVL--AGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTD 3792
            ..|.|.|.|.|.|::.|.|.|:::  :.:.||.| |:...|.|.....||.|.|.|.|.|||||.
Worm  3876 ITLFCNASGNPYPQLKWAKGGSLIFDSPDGARIS-LKGARLDIPHLKKTDVGDYTCQALNAAGTS 3939

Human  3793 RRRIDLQVHVPPSIAPGPTNMTVIVNVQ--TTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRL 3855
            ...:.:.|.|||.|.....:|:..:..|  .||.|.|.|.|.|.:.|..||..|.  .:.....:
Worm  3940 EASVSVDVLVPPEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALT--HSTPGITV 4002

Human  3856 LSSGSLV-IISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCT 3919
            .|..:.: |.:.|:.|...|.|...|.||.|....::.|...|.|::..|..::.... |||.|.
Worm  4003 ASDSTFIQINNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVISNGGTKQVIEGEL-AVIECL 4066

Human  3920 ASGVPFPSIHWTKNGIRLLPRGDGYRILSSG-AIEILATQLNHAGRYTCVARNAAGSAHRHVTLH 3983
            ..|.|.|.:.|.:||.|:.....|.|.::.| .:.|:..:...:|.|.|.|.|.||||.:..||.
Worm  4067 VEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAYTLE 4131

Human  3984 V-HEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISR 4047
            | ..|.:|...|..|.....:...|||...|.|.|.|:|...|.::......|.:...|.|.|.:
Worm  4132 VLVSPKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEK 4196

Human  4048 AVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPIT-LSCEADGLPPPDIT 4111
            | .|....|.|.|:|.||....:..:...|.|.||.....|:...:...| :.||.:. ...:.:
Worm  4197 A-EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES-ESSEFS 4259

Human  4112 WHKDGRAIVESIRQRVLSSG--SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRST 4174
            |.|:|..::.| ...:.|..  .::|...:..|.|.|:|.|||.||:::..|.|.|.|.|:|...
Worm  4260 WSKNGVPLLPS-NNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQKTNLNVGVAPKIMER 4323

Human  4175 EGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE-LILENVVLEDSGFYT 4238
            .....|::..|..|.|.|.|:|.|||.|.|||.||.|.....||....: :|..::....:|.||
Worm  4324 PRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSVIFSSISPSQAGVYT 4388

Human  4239 CVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH 4303
            |.|.|........:.|.|.:.|.......:||.|..:.:.|||.|||||.|.::|..::||...:
Worm  4389 CKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQN 4453

Human  4304 FD--SVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSN-WIEPLGG 4365
            .:  .:.| :.|.|..|..:|.|.|.|.|::..|...|...:.|.:|    .|.|:. |:|
Worm  4454 NEKYQILG-TTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP----SDRPAPIWVE---- 4509

Human  4366 NAILNCEVKGDPTPT----------------IQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDA 4414
                 |:.||.|..|                :.|.    |:|.|..     |||:|
Worm  4510 -----CDEKGKPKKTEYMIDRGDTPDDNPQLLPWK----DVEDSSL-----NGSIA--------- 4551

Human  4415 GDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHS 4479
              |.|:....:     |.::.|.:.|...::|..|....|..:.|.|.|.|.|.|||||::.|..
Worm  4552 --YRCMPGPRS-----SRTVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKL 4609

Human  4480 ISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQVHGGFSQWSAWRACSVT 4544
            |  :|....::.:.|.:......|:.|:.|:|:|.:||..|               ||:
Worm  4610 I--EDSKFEIAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTV---------------SAF------ 4651

Human  4545 CGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDGSWSEWSLWEECTRSCGRGNQTR 4609
                |...:.:...|.|::..|     ::.:..|..:    :.::|....||
Worm  4652 ----INVDNNILPTPKPSSNQK-----NVAVITCYER----NQAYSRGLTWE------------- 4690

Human  4610 TRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPP 4674
                      :.|.|...|...|...|                                  |...
Worm  4691 ----------YNGVPMPKNLAGIHFMN----------------------------------NGSL 4711

Human  4675 PAFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKC 4739
            .....|.....:.::..|..||                        |:|
Worm  4712 VILDTSSLKEGDLELYTCKVRN------------------------RRR---------------- 4736

Human  4740 EGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQ 4804
                      :|.|..|    |.:.|            :...:|.|....:||       ||.:.
Worm  4737 ----------HSIPHLT----SAFEG------------VPEVKTIDKVEVNNG-------DSVVL 4768

Human  4805 RCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACP 4869
            .|                           |.|...|..|.|..|..:....|..      :...|
Worm  4769 DC---------------------------EVTSDPLTTHVVWTKNDQKMLDDDA------IYVLP 4800

Human  4870 GGPQRARGSVIGNINDVEFGIAFLNATITDSPNSDTRIIRAKITNVPRSLGSAMRKIVSILNPIY 4934
            .     ...|:.|:...:.|:                                 .|.|:
Worm  4801 N-----NSLVLLNVEKYDEGV---------------------------------YKCVA------ 4821

Human  4935 WTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEILQMSHIARGLDSDGSLLLDIVVSGYVLQLQS 4999
               :..||:|.:           :||:....|:.|.::    |.:..|..:.|...:|     .|
Worm  4822 ---SNSIGKAFD-----------DTQLNVYEGDFLPLT----GFEGSGINIDDSSNAG-----GS 4863

Human  5000 PAEVTVKDYTEDYIQTGPGQLYAYSTRLFTIDGISIPYTWNHTVFYDQAQGRMPFLVETLHASSV 5064
            ......|...||...|      ..:|...|......|.|  .|:        :|.|: ||.|...
Worm  4864 SRREAYKKENEDASTT------TITTTSPTTTTTETPLT--TTI--------IPALI-TLPAKQY 4911

Human  5065 ES-DYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTY 5128
            .: ||::               |..::        |..||  ..:|.....||..|...:.:.|
Worm  4912 PTDDYHE---------------GSAND--------DGFGP--TTQDSLFEFNPPLHPEISVVNT- 4950

Human  5129 YCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDI 5193
                                              ||..||.
Worm  4951 ----------------------------------DCAGTIN------------------------ 4957

Human  5194 NECQESSPCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLC 5258

Worm  4958 ----------------------------------------------------------------- 4957

Human  5259 PNGMTKAENGTCIDIDECKDG-THQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQV 5322
                   |||.|:|    ||| ||..:.
Worm  4958 -------ENGDCVD----KDGKTHNLKI------------------------------------- 4974

Human  5323 PKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 5387
                                    |.|:
Worm  4975 ------------------------LTGE------------------------------------- 4978

Human  5388 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDT--CVDIDECENTDACQHECKNTF 5450
                :|                         ||||...:..|  |.|:|||.....|..||.|..
Worm  4979 ----NH-------------------------CPEGFAMNPHTRICEDLDECAFYQPCDFECINYD 5014

Human  5451 GSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQR-DPVSG 5514
            |.:||.||.||:|...|  |:|::||  ::|.|...:.|||..|.|:|||.|||.||.. |.
Worm  5015 GGFQCNCPLGYELAEEG--CRDVNEC--ESVRCEDGKACFNQLGGYECIDDPCPANYSLVDD--- 5072

Human  5515 FCLKNCPPNDLECALSPYALEYKLVSLPFGIATNQDLIRLVAYTQDGVMHPRTTFLMVDEEQTV- 5578
               :.|.|....|..:|  ::..::::|.|:..:. :..|.||.:.|.:...||:.:.|....:
Worm  5073 ---RYCEPECENCTSTP--IQVHMLAIPSGLPISH-IATLTAYDKSGRVLNDTTYAISDTGAPLA 5131

Human  5579 -------PFALRDENLKGV------VYTTRPLREAETYRMRVRASSYSANGTIE--YQTTFIVYI 5628
                   ||     .:|.|      |:|.|.|...:.:::||||.|..|...:.  .:|.|:|.|
Worm  5132 RGRMTSGPF-----TIKAVKRGHAQVWTNRVLAAGDHHKVRVRAHSDHATNELHAPKETNFLVLI 5191

Human  5629 AVSAYPY 5635
            .|..||:
Worm  5192 NVGQYPF 5198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HMCN1	NP_114141.2	VWA_2	42..212	CDD:290253	101/169 (60%)
		IG_like	440..512	CDD:214653	19/73 (26%)
		Ig	451..510	CDD:299845	19/60 (32%)
		IG	526..608	CDD:214652	28/81 (35%)
		IGc2	533..593	CDD:197706	20/59 (34%)
		I-set	612..696	CDD:254352	25/84 (30%)
		Ig	626..696	CDD:299845	20/70 (29%)
		IG	708..789	CDD:214652	31/82 (38%)
		Ig	720..786	CDD:143165	26/67 (39%)
		Ig	792..884	CDD:299845	29/97 (30%)
		I-set	793..884	CDD:254352	29/96 (30%)
		I-set	890..977	CDD:254352	32/87 (37%)
		IGc2	903..967	CDD:197706	24/64 (38%)
		Ig	980..1071	CDD:299845	32/114 (28%)
		IG	1086..1167	CDD:214652	23/134 (17%)
		Ig	1086..1167	CDD:299845	23/134 (17%)
		I-set	1171..1258	CDD:254352	32/87 (37%)
		Ig	1188..1256	CDD:299845	26/67 (39%)
		Ig	1261..1357	CDD:299845	28/95 (29%)
		IG_like	1276..1355	CDD:214653	23/78 (29%)
		IG_like	1369..1448	CDD:214653	24/79 (30%)
		IGc2	1382..1438	CDD:197706	18/56 (32%)
		I-set	1452..1542	CDD:254352	30/183 (16%)
		Ig	1460..1542	CDD:299845	30/175 (17%)
		IG	1556..1635	CDD:214652	23/78 (29%)
		Ig	1557..1635	CDD:299845	23/77 (30%)
		I-set	1647..1729	CDD:254352	23/87 (26%)
		Ig	1648..1725	CDD:299845	21/82 (26%)
		IGc2	1752..1812	CDD:197706	19/62 (31%)
		IG_like	1843..1915	CDD:214653	18/71 (25%)
		IGc2	1843..1905	CDD:197706	15/61 (25%)
		IG	1929..2008	CDD:214652	28/78 (36%)
		Ig	1934..2008	CDD:299845	26/73 (36%)
		Ig	2031..2092	CDD:299845	16/68 (24%)
		I-set	2111..2191	CDD:254352	29/85 (34%)
		IGc2	2119..2181	CDD:197706	23/67 (34%)
		I-set	2203..2286	CDD:254352	21/82 (26%)
		Ig	<2222..2277	CDD:299845	16/54 (30%)
		IG_like	2299..2380	CDD:214653	30/83 (36%)
		Ig	2299..2370	CDD:299845	27/73 (37%)
		I-set	2391..2474	CDD:254352	28/87 (32%)
		IGc2	2400..2464	CDD:197706	19/68 (28%)
		I-set	2478..2567	CDD:254352	28/90 (31%)
		IGc2	2493..2557	CDD:197706	23/64 (36%)
		I-set	2582..2663	CDD:254352	25/86 (29%)
		IGc2	2594..2653	CDD:197706	20/63 (32%)
		I-set	2681..2762	CDD:254352	31/80 (39%)
		IGc2	2689..2752	CDD:197706	25/62 (40%)
		IG_like	2789..2865	CDD:214653	27/83 (33%)
		IGc2	2791..2855	CDD:197706	23/71 (32%)
		I-set	2879..2960	CDD:254352	27/80 (34%)
		Ig	2879..2950	CDD:299845	24/70 (34%)
		Ig	2963..3054	CDD:299845	34/92 (37%)
		I-set	2970..3052	CDD:254352	30/83 (36%)
		I-set	3066..3147	CDD:254352	25/80 (31%)
		IGc2	3073..3137	CDD:197706	21/63 (33%)
		I-set	3151..3241	CDD:254352	32/91 (35%)
		IGc2	3167..3228	CDD:197706	24/61 (39%)
		Ig	3244..3338	CDD:299845	27/93 (29%)
		I-set	3252..3336	CDD:254352	21/83 (25%)
		I-set	3356..3430	CDD:254352	23/73 (32%)
		IGc2	3357..3420	CDD:197706	20/62 (32%)
		Ig	3433..3523	CDD:299845	22/90 (24%)
		IG_like	3443..3523	CDD:214653	18/80 (23%)
IG_like	3536..3616	CDD:214653	29/83 (35%)
IGc2	3543..3606	CDD:197706	24/66 (36%)
I-set	3628..3709	CDD:254352	25/80 (31%)
IGc2	3636..3699	CDD:197706	20/62 (32%)
I-set	3719..3800	CDD:254352	27/82 (33%)
Ig	3719..3795	CDD:299845	27/77 (35%)
I-set	3804..3893	CDD:254352	25/91 (27%)
Ig	3810..3883	CDD:299845	20/75 (27%)
Ig	3896..3984	CDD:299845	29/88 (33%)
IG_like	3903..3984	CDD:214653	27/81 (33%)
Ig	3987..4067	CDD:299845	25/79 (32%)
IG	3994..4075	CDD:214652	23/80 (29%)
I-set	4079..4165	CDD:254352	24/88 (27%)
IGc2	4093..4155	CDD:197706	16/64 (25%)
Ig	4168..4258	CDD:299845	30/90 (33%)
IG_like	4176..4256	CDD:214653	27/80 (34%)
I-set	4260..4345	CDD:254352	27/86 (31%)
IGc2	4274..4335	CDD:197706	21/62 (34%)
IG	4356..4435	CDD:214652	19/95 (20%)
Ig	4356..4435	CDD:299845	19/95 (20%)
I-set	4440..4526	CDD:254352	26/85 (31%)
Ig	4443..4521	CDD:299845	24/77 (31%)
TSP1	4533..4584	CDD:214559	7/50 (14%)
TSP1	4589..4641	CDD:214559	8/51 (16%)
TSP1	4646..4698	CDD:214559	5/51 (10%)
TSP1	4703..4755	CDD:214559	4/51 (8%)
TSP1	4760..4812	CDD:214559	9/51 (18%)
TSP1	4817..4869	CDD:214559	7/51 (14%)
G2F	4868..5092	CDD:214774	35/224 (16%)
EGF_CA	5107..5146	CDD:214542	5/38 (13%)
EGF_CA	5147..5190	CDD:284955	4/42 (10%)
EGF_CA	5192..5228	CDD:214542	0/35 (0%)
EGF_CA	5230..5263	CDD:238011	0/32 (0%)
EGF_CA	5272..5313	CDD:284955	6/41 (15%)
EGF_CA	5315..5354	CDD:214542	2/38 (5%)
EGF_CA	5432..5471	CDD:214542	17/38 (45%)
EGF_CA	5472..5508	CDD:214542	17/35 (49%)
him-4	NP_001024582.1	IG_like	442..515	CDD:214653	20/73 (27%)
		IG	527..605	CDD:214652	27/78 (35%)
		Ig	628..694	CDD:319273	20/65 (31%)
		I-set	702..789	CDD:369462	33/88 (38%)
		I-set	793..881	CDD:369462	29/96 (30%)
		Ig	899..974	CDD:386229	29/76 (38%)
		I-set	1012..1081	CDD:369462	25/68 (37%)
		Ig	1109..1172	CDD:319273	7/62 (11%)
		Ig	1196..1263	CDD:319273	18/66 (27%)
		IG_like	1277..1358	CDD:214653	29/80 (36%)
		I-set	1373..1450	CDD:369462	23/77 (30%)
		Ig	1474..1544	CDD:386229	23/69 (33%)
		IGc2	1563..1628	CDD:197706	12/64 (19%)
		Ig	1651..1732	CDD:386229	17/80 (21%)
		Ig	1755..1818	CDD:319273	21/65 (32%)
		Ig	1839..1912	CDD:386229	22/84 (26%)
		Ig	1930..2002	CDD:386229	22/74 (30%)
		IG_like	2014..2095	CDD:214653	21/80 (26%)
		Ig	2094..2182	CDD:386229	32/89 (36%)
		Ig	2190..2283	CDD:386229	23/96 (24%)
		I-set	2296..2380	CDD:369462	29/85 (34%)
		Ig	2384..2471	CDD:386229	25/92 (27%)
		IGc2	2492..2556	CDD:197706	24/63 (38%)
		Ig	2580..2654	CDD:386229	22/74 (30%)
		Ig	2686..2753	CDD:319273	24/66 (36%)
		IG_like	2768..2850	CDD:214653	25/84 (30%)
		I-set	2854..2939	CDD:369462	33/95 (35%)
		IG_like	2951..3031	CDD:214653	28/96 (29%)
		I-set	3046..3116	CDD:369462	26/72 (36%)
		I-set	3127..3213	CDD:369462	32/89 (36%)
		Ig	3217..3292	CDD:386229	27/86 (31%)
		I-set	3300..3386	CDD:369462	32/91 (35%)
		I-set	3396..3472	CDD:369462	27/90 (30%)
		I-set	3481..3569	CDD:369462	29/92 (32%)
		I-set	3591..3663	CDD:369462	18/71 (25%)
		Ig	3667..3762	CDD:386229	32/97 (33%)
		Ig	3775..3848	CDD:386229	23/74 (31%)
		Ig	3859..3947	CDD:386229	28/88 (32%)
		IGc2	3968..4031	CDD:197706	18/64 (28%)
		Ig_3	4045..4119	CDD:372822	22/74 (30%)
		Ig_3	4136..4210	CDD:372822	22/74 (30%)
		Ig	<4262..4314	CDD:386229	16/52 (31%)
		Ig	4318..4406	CDD:386229	29/87 (33%)
		IG_like	4418..4496	CDD:214653	26/78 (33%)
		I-set	4570..4654	CDD:369462	29/110 (26%)
		I-set	4752..4836	CDD:369462	25/181 (14%)
		EGF_CA	4996..5027	CDD:238011	15/30 (50%)
		EGF_CA	5034..5076	CDD:214542	19/49 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	342	1.000	Domainoid score	I623
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23741
Inparanoid	1	1.050	2007	1.000	Inparanoid score	I12
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45417
OrthoDB	1	1.010	-	-		D26097at33208
OrthoFinder	1	1.000	-	-		FOG0004818
OrthoInspector	1	1.000	-	-		otm16411
orthoMCL	1	0.900	-	-		OOG6_100287
Panther	1	1.100	-	-	O	PTHR23277
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R9218
SonicParanoid	1	1.000	-	-		X2879
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	13.010