Protein Alignment Tnk1 and Src42A

DIOPT Version :10

• Sequence 1: NP_114086.3
• Gene: Tnk1 / 83813
• MGIID: 1930958
• Length: 666
• Species: Mus musculus
• Sequence 2: NP_001400996.1
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1606
• Species: Drosophila melanogaster
• Alignment Length: 274
• Identity: 99/274 - (36%)
• Similarity: 141/274 - (51%)
• Gaps: 30/274 - (10%)

Mouse   122 LGSGCFGVVHRGLWTLPSGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGL 186
            ||||.||.|..|||    ..:.|||:|:|:.|...|.     |||.|..:|.||.|..:::|:.:
  Fly  1343 LGSGQFGDVWEGLW----NNTTPVAIKTLKSGTMDPK-----DFLAEAQIMKKLRHTKLIQLYAV 1398

Mouse   187 -VLGQPLQMVMELAPLGSLHARLTAPA-PTPPLPVALLCLFLRQLAGAMAYLGSCGLVHRDLATR 249
             .:.:|:.::.||...|||...|.|.| ....|.:..|.....|:|..||||.|...:|||||.|
  Fly  1399 CTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAAR 1463

Mouse   250 NLLLASPRMIKVADFGLVRPLG--------GARGRYVMGGPRPIPYAWCAPESLRQGAFSSASDV 306
            |:|:....::|:|||||.|.:.        |||          .|..|.|||:.....||..|||
  Fly  1464 NVLVGDGNIVKIADFGLARLIKEDEYEARVGAR----------FPIKWTAPEAANYSKFSIKSDV 1518

Mouse   307 WMFGVTLWEMFSGGEEPWAGVPPYLILQRLEKDRARLPKPPLCSRALYSLALRCWAPHPADRPSF 371
            |.||:.|.|:.:.|..|:.|:....:|.::|.. .|:|:||.|...||.:.|.||...|..||:|
  Fly  1519 WSFGILLTELVTYGRIPYPGMTNAEVLTQVEHG-YRMPQPPNCEPRLYEIMLECWHKDPMRRPTF 1582

Mouse   372 SNLEGLLQEAWLSE 385
            ..|:..|::.:.|:
  Fly  1583 ETLQWKLEDFYTSD 1596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tnk1	NP_114086.3	SAM_TNK-like	16..67	CDD:188938
		Protein Kinases, catalytic domain	120..380	CDD:473864	98/267 (37%)
		SH3	<395..436	CDD:473055
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	442..589
		UBA_like_SF	594..637	CDD:473871
		UBA_like_SF	624..663	CDD:473871
Src42A	NP_001400996.1	SH2_Src_Src42	1210..1301	CDD:198233
		PTKc_Frk_like	1328..1596	CDD:270653	98/272 (36%)