DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tnk1 and Btk

DIOPT Version :10

Sequence 1:NP_114086.3 Gene:Tnk1 / 83813 MGIID:1930958 Length:666 Species:Mus musculus
Sequence 2:NP_476745.1 Gene:Btk / 34132 FlyBaseID:FBgn0003502 Length:786 Species:Drosophila melanogaster


Alignment Length:84 Identity:15/84 - (17%)
Similarity:24/84 - (28%) Gaps:36/84 - (42%)


- Green bases have known domain annotations that are detailed below.


Mouse   317 FRDATQGFTDFSRTESMTQEGLPE----------FVTAMSRCSTDDDF----------------- 354
            :...|:.......|:|:.:...|.          ||         |||                 
  Fly    10 YNGTTEPLLSLPNTQSLIEPQTPTIPEIYFFILFFV---------DDFEADLGLGHMDFQSIQML 65

Mouse   355 GDTDTLKDFKEEDELAEEM 373
            .||.|:.|..:||....::
  Fly    66 SDTSTMIDPMDEDSFRRDL 84

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tnk1NP_114086.3 SAM_TNK-like 16..67 CDD:188938
Protein Kinases, catalytic domain 120..380 CDD:473864 15/84 (18%)
SH3 <395..436 CDD:473055
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 442..589
UBA_like_SF 594..637 CDD:473871
UBA_like_SF 624..663 CDD:473871
BtkNP_476745.1 PH_Btk 44..222 CDD:269944 11/50 (22%)
SH3_Tec_like 346..399 CDD:212702
SH2_Tec_family 403..505 CDD:198188
PTKc_Tec_like 521..778 CDD:173637
Blue background indicates that the domain is not in the aligned region.

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