Protein Alignment KCNK16 and Task7

DIOPT Version :10

• Sequence 1: NP_001128577.1
• Gene: KCNK16 / 83795
• HGNCID: 14464
• Length: 322
• Species: Homo sapiens
• Sequence 2: NP_649891.1
• Gene: Task7 / 41125
• FlyBaseID: FBgn0037690
• Length: 340
• Species: Drosophila melanogaster
• Alignment Length: 209
• Identity: 74/209 - (35%)
• Similarity: 108/209 - (51%)
• Gaps: 11/209 - (5%)

Human    13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEAW 77
            |.|.|::....|||:||.:|..||...||:..:..|..|..|:..|...|    |.|  .:||..
  Fly     8 RTLSLVVCTFTYLLIGAAVFDSLESPTEAKRWEFLQTVKNNFVRKYNVTD----EDF--RVMEIV 66

Human    78 VKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNH 142
            :  :..|.:...| .|.|..:|:|:..|:..||||:..|.|..|:.||:.||::||||.::....
  Fly    67 I--IENKPHKAGP-QWKFAGAFYFSTVVLAMIGYGHSTPVTIPGKAFCMGYAMVGIPLGLVMFQS 128

Human   143 LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTL--VILIFPPMVFSHVEGWSFSEGFYF 205
            :|..|....:.|.|...|...::......:.|.|..|.|  :|:.....|||..||||:.:.||:
  Fly   129 IGERLNKFASVIIRRAKRASGARCTDATEMNLMLATGMLSSIIITTGAAVFSRYEGWSYFDSFYY 193

Human   206 AFITLSTIGFGDYV 219
            .|:||:||||||||
  Fly   194 CFVTLTTIGFGDYV 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNK16	NP_001128577.1	Ion_trans_2	87..145	CDD:462301	21/57 (37%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	108..113		3/4 (75%)
		Ion_trans_2	180..>219	CDD:462301	20/40 (50%)
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	212..217		4/4 (100%)
Task7	NP_649891.1	Ion_trans_2	<74..133	CDD:462301	22/59 (37%)
		Ion_trans_2	166..244	CDD:462301	22/42 (52%)