Protein Alignment KCNK16 and CG1688

DIOPT Version :10

• Sequence 1: NP_001128577.1
• Gene: KCNK16 / 83795
• HGNCID: 14464
• Length: 322
• Species: Homo sapiens
• Sequence 2: NP_610516.1
• Gene: CG1688 / 36005
• FlyBaseID: FBgn0027589
• Length: 918
• Species: Drosophila melanogaster
• Alignment Length: 214
• Identity: 60/214 - (28%)
• Similarity: 98/214 - (45%)
• Gaps: 52/214 - (24%)

Human     2 PSAGLCSCWGGRVLPLL-------LAYVCYLLLGATIFQLLE-------RQAEAQSRDQ------ 46
            |.:.|..|. |.:|.||       |..:.|.:||..:|.|||       ..|.|:||:.
  Fly    58 PRSSLRRCC-GHLLKLLFSTPGLVLLVIGYSVLGGLLFPLLEAPQDISKSAAIAKSREDCLRELW 121

Human    47 FQLEKLRFL--ENYTCLDQWAMEQFVQVIMEAWVK-----------GVNPKGNST---------- 88
            ...|||..|  .|:|.|....:.:|...|:.|..:           |:..:|:::
  Fly   122 IITEKLNVLYERNWTMLVHEQLRRFEGSIVAATRQGSAGSSGGGGAGLFHEGSASALGHFGYDAG 186

Human    89 NPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHL-- 151
            :..:|.|..:..::.||:||||:|:|.|.|.||::..:||||:|:||.::.|:.||..|...|
  Fly   187 DSQSWSFSEALLYSVTVITTIGHGSLTPRTAAGKLATIFYALVGVPLMLMCLSSLGALLADGLQC 251

Human   152 ------AAIERWEDRPRRS 164
                  ..::|.::..|:|
  Fly   252 TYVRLCCQLQRHQEHRRKS 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNK16	NP_001128577.1	Ion_trans_2	87..145	CDD:462301	23/67 (34%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	108..113		3/4 (75%)
		Ion_trans_2	180..>219	CDD:462301
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	212..217
CG1688	NP_610516.1	Ion_trans_2	177..247	CDD:462301	25/69 (36%)
		Ion_trans_2	822..896	CDD:462301