Sequence 1: | NP_001013858.1 | Gene: | MAD1L1 / 8379 | HGNCID: | 6762 | Length: | 718 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_610477.2 | Gene: | Mad1 / 35954 | FlyBaseID: | FBgn0026326 | Length: | 730 | Species: | Drosophila melanogaster |
Alignment Length: | 740 | Identity: | 188/740 - (25%) |
---|---|---|---|
Similarity: | 348/740 - (47%) | Gaps: | 103/740 - (13%) |
- Green bases have known domain annotations that are detailed below.
Human 15 RSLNNFISQRVEGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRSKSHLIQVEREKMQMELSHK 79
Human 80 RARVELERAASTSARNYEREVDRNQELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKR 144
Human 145 LR-----EKEDSLAQAGETINALKGRISELQWSVMDQEMRV-KRLESEKQELQEQLDLQHKKCQE 203
Human 204 ANQKIQELQAS--QEARADHEQQIKDLE------QKLSLQEQDAA----IVKNMKSELVRLPRLE 256
Human 257 RELKQLREESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETLVGLELENERLLAKLQSWERL- 320
Human 321 -DQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSARGLEKARQQLQEE----LRQVSGQL 380
Human 381 LEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKV 445
Human 446 HSHSAEMEAQLSQALEE--LGGQKQRADMLEMELKMLKSQ---SSSAEQSFLFSREEADTLRLKV 505
Human 506 EELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECER 570
Human 571 LRGLLRAMERGGTVPADLEAAAASLPSS-------KEVAELKKQVESAELKNQRLKEVFQTKIQE 628
Human 629 FRKACYTLTGYQID-ITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEV 692
Human 693 HLRRQDSIPAFLSSLTLELFSRQTV 717 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
MAD1L1 | NP_001013858.1 | MAD | 54..716 | CDD:283261 | 176/698 (25%) |
Nuclear localization signal. /evidence=ECO:0000269|PubMed:19010891 | 79..82 | 1/2 (50%) | |||
Important for interaction with IK. /evidence=ECO:0000269|PubMed:22351768 | 301..340 | 6/40 (15%) | |||
Necessary for interaction with NEK2. /evidence=ECO:0000269|PubMed:14978040 | 380..532 | 39/156 (25%) | |||
Important for interaction with IK. /evidence=ECO:0000269|PubMed:22351768 | 439..480 | 10/42 (24%) | |||
Necessary for interaction with MAD2L1. /evidence=ECO:0000269|PubMed:19010891 | 540..551 | 6/10 (60%) | |||
Mad1 | NP_610477.2 | MAD | 80..726 | CDD:283261 | 176/698 (25%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 1 | 1.000 | 197 | 1.000 | Domainoid score | I3109 |
eggNOG | 1 | 0.900 | - | - | E1_KOG4593 | |
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 1 | 1.000 | - | - | H74500 | |
Inparanoid | 1 | 1.050 | 200 | 1.000 | Inparanoid score | I3790 |
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D483557at33208 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0004279 | |
OrthoInspector | 1 | 1.000 | - | - | oto89647 | |
orthoMCL | 1 | 0.900 | - | - | OOG6_103958 | |
Panther | 1 | 1.100 | - | - | LDO | PTHR23168 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R676 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
12 | 11.900 |