Protein Alignment SLC25A18 and CG7943

DIOPT Version :10

• Sequence 1: NP_113669.1
• Gene: SLC25A18 / 83733
• HGNCID: 10988
• Length: 315
• Species: Homo sapiens
• Sequence 2: NP_651766.1
• Gene: CG7943 / 43574
• FlyBaseID: FBgn0039741
• Length: 332
• Species: Drosophila melanogaster
• Alignment Length: 277
• Identity: 62/277 - (22%)
• Similarity: 98/277 - (35%)
• Gaps: 84/277 - (30%)

Human    11 KLINGGV-------------------AGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTA 56
            ||::|.|                   |..|.:...:||           .|.:::.|:..:..|:
  Fly    37 KLLHGSVFSKRFFGSFQWEEFACGCGAAFVNIAVTYPI-----------YKMIFRQMLHGVPITS 90

Human    57 -----RAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQ 116
                 |.||...:|||....|...|...:|.....|..||.|:||....:...::||...||..:
  Fly    91 AFAQLRHEGLGFLYRGMLPPLAQKTISLSIMFGVFDGTRRYLVEDYRLNDYGAKVLAAVVAGSAE 155

Human   117 VVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAG 181
            .:: .|.|.::..|.|    :..||..::..:..| |.   .|.|                |...
  Fly   156 SIL-LPFERVQTLLAD----SKFHQHFSNTQNAFR-YV---VSHH----------------GYRE 195

Human   182 LYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASF------------AHSFVSGCVAGSI 234
            |||||.....|:            .|:|..|..|..:||.            ...|::|.|.|:.
  Fly   196 LYRGLEPVFWRN------------GLSNALFFVLREEASVRLPKRKSVSTRTVQEFIAGAVIGAS 248

Human   235 AAVAVTPLDVLKTRIQT 251
            .:....||:|:|..:|:
  Fly   249 ISTIFYPLNVIKVSLQS 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A18	NP_113669.1	Mito_carr	4..97	CDD:395101	25/109 (23%)
		Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	6..92		22/104 (21%)
		Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	100..210		22/109 (20%)
		Mito_carr	106..204	CDD:395101	21/97 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	141..160		3/18 (17%)
		Mito_carr	217..302	CDD:395101	11/47 (23%)
		Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	219..308		11/45 (24%)
CG7943	NP_651766.1	Mito_carr	54..136	CDD:395101	21/92 (23%)
		Mito_carr	141..229	CDD:395101	27/124 (22%)
		Mito_carr	235..322	CDD:395101	9/31 (29%)