Protein Alignment SLC25A18 and CG2616

DIOPT Version :10

• Sequence 1: NP_113669.1
• Gene: SLC25A18 / 83733
• HGNCID: 10988
• Length: 315
• Species: Homo sapiens
• Sequence 2: NP_649731.1
• Gene: CG2616 / 40915
• FlyBaseID: FBgn0037512
• Length: 449
• Species: Drosophila melanogaster
• Alignment Length: 351
• Identity: 85/351 - (24%)
• Similarity: 143/351 - (40%)
• Gaps: 98/351 - (27%)

Human    11 KLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKA-------------------------------M 44
            ::|:.....::....:.|:|:.|||:|:|...|                               .
  Fly    93 QVISACTGAMITACFMTPLDVIKTRMQSQQSPAHKCFFYSNGLMDHLFASGPNGSELASLRQRPQ 157

Human    45 YKGMIDCLMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLME--------DGMQRN 101
            :....|.|||.:|.||...::.|....|....|...|...|.:.|:...::        ....|:
  Fly   158 FSSSWDALMKISRHEGLAALWSGLGPTLVSALPSTIIYFVAYEQFKARYLQIYESHYNKSQEPRH 222

Human   102 LKME-----------MLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTT 155
            |::.           |::|..|.:|.|.|..|:|:::.::|
  Fly   223 LEIRDTKKSLPSVVPMMSGVTARICAVTVVSPIELVRTKMQ------------------------ 263

Human   156 GSASTHRRPSATLIAW--ELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANL-NNLGFNELAG 217
                ..|:..|.::.:  .::..||:.||:|||..|:|||:|||.||:|::.:| .|||.   ..
  Fly   264 ----AQRQTYAQMLQFVRSVVALQGVWGLWRGLRPTILRDVPFSGIYWPIYESLKQNLGH---GS 321

Human   218 KASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMY---SGITDCARK--------L 271
            :.||:.||::|.:||::||:..||.||:||..|.   ..||.:.   |...|..:|        :
  Fly   322 QPSFSLSFLAGVMAGTVAAIVTTPFDVVKTHEQI---EFGERVIFTDSPARDFGKKSTFSRLTGI 383

Human   272 WIQEGPSAFMKGAGCRALVIAPLFGI 297
            :...|......|.|.|.|.:||...|
  Fly   384 YRTHGVRGLFAGCGPRLLKVAPACAI 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A18	NP_113669.1	Mito_carr	4..97	CDD:395101	22/124 (18%)
		Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	6..92		22/111 (20%)
		Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	100..210		31/123 (25%)
		Mito_carr	106..204	CDD:395101	28/99 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	141..160		0/18 (0%)
		Mito_carr	217..302	CDD:395101	29/92 (32%)
		Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	219..308		29/90 (32%)
CG2616	NP_649731.1	Mito_carr	86..207	CDD:395101	22/113 (19%)
		Mito_carr	230..321	CDD:395101	32/121 (26%)
		Mito_carr	321..425	CDD:395101	29/92 (32%)