DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC25A18 and Bmcp

DIOPT Version :10

Sequence 1:NP_113669.1 Gene:SLC25A18 / 83733 HGNCID:10988 Length:315 Species:Homo sapiens
Sequence 2:NP_648501.1 Gene:Bmcp / 39322 FlyBaseID:FBgn0036199 Length:303 Species:Drosophila melanogaster


Alignment Length:302 Identity:82/302 - (27%)
Similarity:126/302 - (41%) Gaps:65/302 - (21%)


- Green bases have known domain annotations that are detailed below.


Human    13 INGGVAGLVGVTCVFPIDLAKTRLQNQHGK-------AMYKGMIDCLMKTARAEGFFGMYRG--- 67
            :.||||.:......||||..|||||.|..|       ..|:||.|..:|.:|.||...:|.|   
  Fly    11 VYGGVASITAEFGTFPIDTTKTRLQIQGQKIDQSFSQLRYRGMTDAFVKISREEGLRALYSGIWP 75

Human    68 -----AAVNLTLVTPEKAIKLAANDFFRRLLM-EDGMQRNLKMEMLAGCGAGMCQVVVTCPMEML 126
                 |............:|..||:  |.||: |||.:| :...:|....||.....:..|.::|
  Fly    76 AVLRQATYGTIKFGTYYTLKKLANE--RGLLINEDGSER-VWSNILCAAAAGAISSAIANPTDVL 137

Human   127 KIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLL 191
            |:::|..|:  ..|:|....                       ..|:.:.:|:.||:||:|.|..
  Fly   138 KVRMQVHGK--GQHKGLLGC-----------------------FGEIYKYEGVRGLWRGVGPTAQ 177

Human   192 RDIPFSIIYFPLF----ANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQ-- 250
            |.:..:.:..|::    ..|.| .|.:..|     :.|:|..:|...:|:|.||:||::||:.  
  Fly   178 RAVVIASVELPVYDFCKLQLMN-AFGDHVG-----NHFISSFIASLGSAIASTPIDVIRTRLMNQ 236

Human   251 ---------TLKKGLGEDMYSGITDCARKLWIQEGPSAFMKG 283
                     .:.......:|||..|||.:....||..|..||
  Fly   237 RPVSITMNGVVTAAATPKLYSGSLDCAVQTIRNEGLPALYKG 278

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC25A18NP_113669.1 Mito_carr 4..97 CDD:395101 33/99 (33%)
Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 6..92 30/93 (32%)
Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 100..210 22/113 (19%)
Mito_carr 106..204 CDD:395101 20/97 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 141..160 1/18 (6%)
Mito_carr 217..302 CDD:395101 23/78 (29%)
Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 219..308 22/76 (29%)
BmcpNP_648501.1 Mito_carr 7..97 CDD:395101 27/85 (32%)
Mito_carr <132..199 CDD:395101 18/91 (20%)
Mito_carr 204..303 CDD:395101 23/80 (29%)

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