Protein Alignment SLC25A18 and sea

DIOPT Version :10

• Sequence 1: NP_113669.1
• Gene: SLC25A18 / 83733
• HGNCID: 10988
• Length: 315
• Species: Homo sapiens
• Sequence 2: NP_001027175.1
• Gene: sea / 3772221
• FlyBaseID: FBgn0037912
• Length: 317
• Species: Drosophila melanogaster
• Alignment Length: 284
• Identity: 79/284 - (27%)
• Similarity: 139/284 - (48%)
• Gaps: 46/284 - (16%)

Human    12 LINGGVAGLVGVTCVFPIDLAKTRLQ-NQHGKA-MYKGMIDCLMKTARAEGFFGMYRGAAVNLTL 74
            ::.||:.|.:.:...:|.:..||:|| ::.|.| .|.|:.||:.||....||.|:|||.:|.:..
  Fly    37 IVAGGITGGIEICITYPTEYVKTQLQLDEKGAAKKYNGIFDCVKKTVGERGFLGLYRGLSVLVYG 101

Human    75 VTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQ-VVVTCPMEMLKIQLQDAGRLAV 138
            ..|:.|.:..|.:|.:...::...|.:...::|.|.|||:|: :|...|||.:|::.       :
  Fly   102 SIPKSAARFGAFEFLKSNAVDSRGQLSNSGKLLCGLGAGVCEAIVAVTPMETIKVKF-------I 159

Human   139 HHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPL 203
            :.|.|.:......::..|               ::::::|::|:|:||..|:|:......|.|.:
  Fly   160 NDQRSGNPKFRGFAHGVG---------------QIIKSEGISGIYKGLTPTILKQGSNQAIRFFV 209

Human   204 FANLNNLGFNE---------LAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGED 259
            ..:|.:|...:         :.|        |.|.:||:.:....|||||:|||:|    ||...
  Fly   210 LESLKDLYKGDDHTKPVPKLVVG--------VFGAIAGAASVFGNTPLDVVKTRMQ----GLEAS 262

Human   260 MYSGITDCARKLWIQEGPSAFMKG 283
            .|.....||.::...|||:||.||
  Fly   263 KYKNTAHCAVEILKNEGPAAFYKG 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A18	NP_113669.1	Mito_carr	4..97	CDD:395101	27/86 (31%)
		Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	6..92		27/81 (33%)
		Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	100..210		24/110 (22%)
		Mito_carr	106..204	CDD:395101	23/98 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	141..160		3/18 (17%)
		Mito_carr	217..302	CDD:395101	26/67 (39%)
		Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282	219..308		25/65 (38%)
sea	NP_001027175.1	Mito_carr	34..117	CDD:395101	27/79 (34%)
		Mito_carr	125..220	CDD:395101	26/116 (22%)
		Mito_carr	235..314	CDD:395101	24/56 (43%)