DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JAM3 and boi

DIOPT Version :9

Sequence 1:	NP_116190.3	Gene:	JAM3 / 83700	HGNCID:	15532	Length:	310	Species:	Homo sapiens
Sequence 2:	NP_001096868.3	Gene:	boi / 31229	FlyBaseID:	FBgn0040388	Length:	1105	Species:	Drosophila melanogaster

Alignment Length:	212	Identity:	55/212 - (25%)
Similarity:	81/212 - (38%)	Gaps:	57/212 - (26%)

- Green bases have known domain annotations that are detailed below.

Human    30 GAVNLKSSNRTPVVQEFESVELSCII--TDSQTSDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRA 92
            |::..:||.|..|..:      :|::  ..|..|:|...|.          |:.|   |....::
  Fly   143 GSMGARSSIRWSVAPK------NCLLIRCGSVISNPPAIWS----------FYRN---GKKLPQS 188

Human    93 EIL--GKTSLKIWNVTRRDSALYRCEVVARN----DRKEIDEIVIELTVQVKPVTP---VCRVP- 147
            |:|  ...:|.:..||.:|:..|.|  ||.|    |...:.: .|||.|.....||   :.|.|
  Fly   189 ELLPGAAGALVLDTVTAKDAGNYSC--VATNSITGDELRLPQ-TIELRVDYTDRTPPYFLQRPPI 250

Human   148 --KAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPR----FRNSSFHLNSETGTLVF 206
              .|.| |:...|.| ...|.|||...|            ::|.    :.|.|..|:.   .|..
  Fly   251 EYSARP-GETVVLEC-PGVGSPRPRVIW------------SSPNVVEIYNNRSTILSY---GLQI 298

Human   207 TAVHKDDSGQYYCIASN 223
            |.|..:|.|.|.|:..|
  Fly   299 TDVKPEDQGSYICMLDN 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JAM3	NP_116190.3	IG	42..135	CDD:214652	24/100 (24%)
JAM3	NP_116190.3	Ig	156..231	CDD:319273	19/72 (26%)
boi	NP_001096868.3	IG_like	42..131	CDD:214653
		IG_like	154..234	CDD:214653	24/101 (24%)
		Ig	172..234	CDD:299845	20/77 (26%)
		IG_like	249..329	CDD:214653	23/84 (27%)
		Ig	257..329	CDD:299845	20/75 (27%)
		IG_like	339..418	CDD:214653
		Ig	352..408	CDD:299845
		FN3	470..592	CDD:238020
		FN3	613..700	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910