DRSC/TRiP Functional Genomics Resources

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Protein Alignment RPS6KL1 and DBF20

DIOPT Version :10

Sequence 1:XP_011535508.1 Gene:RPS6KL1 / 83694 HGNCID:20222 Length:603 Species:Homo sapiens
Sequence 2:NP_015436.1 Gene:DBF20 / 856227 SGDID:S000006315 Length:564 Species:Saccharomyces cerevisiae


Alignment Length:225 Identity:54/225 - (24%)
Similarity:87/225 - (38%) Gaps:68/225 - (30%)


- Green bases have known domain annotations that are detailed below.


Human   408 WAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFG----------------QWSEVE-- 454
            :.:||..|:.||||.|...|||.|.|.|:|..|||:||.||                :..||:  
Yeast   272 YISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERIESMKIRLEEVKNL 336

Human   455 --PQCCGEAVDNL-----------------------YSAPEVGGISELTEACDWWSFGSLLYELL 494
              |.....::::.                       |.|.||....:.....|:||.|.:|:|.|
Yeast   337 EFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVLEGKKYDFTVDYWSLGCMLFESL 401

Human   495 ------TGMALSQSHPSGIQAHTQLQLPEWLSRPAA------SLLTELLQFEPTRRLGMGEGGVS 547
                  :|.:.::::.:.......|:.|....|.||      .|:|.|:. :|..|:...|    
Yeast   402 VGYTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLITRLIA-DPINRVRSFE---- 461

Human   548 KLKSHPFFSTIQWSKLVGALVLLSGTHFPP 577
            :::...:|:.|.:..|        .|..||
Yeast   462 QVRKMSYFAEINFETL--------RTSSPP 483

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RPS6KL1XP_011535508.1 MIT_SNX15 48..122 CDD:239140
STKc_RPK118_like 148..555 CDD:270728 48/201 (24%)
DBF20NP_015436.1 MobB_Sid2p-like 77..164 CDD:439271
STKc_Sid2p_like 157..539 CDD:270751 54/225 (24%)
Blue background indicates that the domain is not in the aligned region.

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