DRSC/TRiP Functional Genomics Resources

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Protein Alignment RPS6KL1 and PKH3

DIOPT Version :10

Sequence 1:XP_011535508.1 Gene:RPS6KL1 / 83694 HGNCID:20222 Length:603 Species:Homo sapiens
Sequence 2:NP_010754.1 Gene:PKH3 / 852077 SGDID:S000002874 Length:898 Species:Saccharomyces cerevisiae


Alignment Length:230 Identity:47/230 - (20%)
Similarity:93/230 - (40%) Gaps:66/230 - (28%)


- Green bases have known domain annotations that are detailed below.


Human   406 KQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAV-------- 462
            :.:.|:::.|||.:|..|::.|||.|.|:|||:.|.:.:|.||..:.::|...|::.        
Yeast   116 RHFTAQLIDALEFIHSHGIIHRDLKPENVLLDRDGRLMITDFGAAATIDPSLSGDSAKFNSDSNG 180

Human   463 --DNL----------YSAPEVGGISELTEACDWWSFGSLLYELLTGMA--LSQSHPSGIQAHTQL 513
              ||.          |.:||:...::.....|.|:.|.::|:.:.|..  ..::.....:....|
Yeast   181 SKDNQNCASFVGTAEYVSPELLLYNQCGYGSDIWALGCMIYQFVQGQPPFRGENELKTFEKIVAL 245

Human   514 QLPEW------------LSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVGA 566
            ..| |            ::....:|:.::|..|...|:.:     .::|.||:||.:.|:..:..
Yeast   246 DYP-WGPNNRINNSTSPINPLVINLVQKILVIEVNERISL-----EQIKRHPYFSKVDWNDKIKI 304

Human   567 LVLLSGTHFPPVTDLHRGMASLQELSRQGLWKRQG 601
            .                          :|:|:.||
Yeast   305 W--------------------------RGIWQSQG 313

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RPS6KL1XP_011535508.1 MIT_SNX15 48..122 CDD:239140
STKc_RPK118_like 148..555 CDD:270728 40/182 (22%)
PKH3NP_010754.1 STKc_PDK1 9..293 CDD:270733 40/182 (22%)
Blue background indicates that the domain is not in the aligned region.

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