DRSC/TRiP Functional Genomics Resources

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Protein Alignment RPS6KL1 and psk1

DIOPT Version :10

Sequence 1:XP_011535508.1 Gene:RPS6KL1 / 83694 HGNCID:20222 Length:603 Species:Homo sapiens
Sequence 2:NP_587830.1 Gene:psk1 / 2539494 PomBaseID:SPCC4G3.08 Length:436 Species:Schizosaccharomyces pombe


Alignment Length:431 Identity:92/431 - (21%)
Similarity:136/431 - (31%) Gaps:180/431 - (41%)


- Green bases have known domain annotations that are detailed below.


Human   157 GVIEKRDLAVLPRLVSNSLPQVQLVQDPATGGTFVVKSLPRCHMV-----------SRERLTIIP 210
            |.:...|...|..|...|..:|.||:...||..|..|.|.:..:|           .|:.|..:.
pombe    84 GKMRPADFQPLTVLGRGSYGKVLLVKQKNTGRLFAQKQLKKASIVLRAKGLEQTKNERQILEEVR 148

Human   211 HGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQAHSRHSGLSSGSTQERMKAQLNPHLNL 275
            |  |::.:|...|...|.::|.|::..||.|:|||               .::||          
pombe   149 H--PFICRLYYAFQDHDRLYLILQYAPGGELFSHL---------------AEQRM---------- 186

Human   276 LTPARLPSGHAPGQDRIALEPPRTSPNLLLAGEAPSTRPQREAEGEPTARTSTSGSSDLPKAPGG 340
                                                                      ||     
pombe   187 ----------------------------------------------------------LP----- 188

Human   341 HLHLQARRAGQNSDAGPPRGLTWVPEGAGPVLGGCGRGMDQSCLSADGAGRGCGRATWSVREEQV 405
                                                                         |:.|
pombe   189 -------------------------------------------------------------EDVV 192

Human   406 KQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFG--QWSEVEPQCCGEAVDNLYSA 468
            ..:.||:.:||..||:.|::.|||.|.|.|||..|||.||.||  :.:|....|........|.|
pombe   193 AFYTAELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGADCRSFVGTEEYCA 257

Human   469 PEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQL---------QLPEWLSRPAA 524
            ||:........|.||||.|.|:::||||     |.|.....|.::         .:|.:::..|.
pombe   258 PEILLEQPYDHAVDWWSMGILIFDLLTG-----SPPFTANNHKRIMEKITRAKPNIPFYVTSDAR 317

Human   525 SLLTELLQFEPTRRLGMG--EGGVSKLKSHPFFSTIQWSKL 563
            .::.:.|:..|.:|||..  |.|...:|.|..:..|.|:||
pombe   318 DIINKFLKKNPKQRLGADGPEKGYDAIKKHRIYRRIDWNKL 358

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RPS6KL1XP_011535508.1 MIT_SNX15 48..122 CDD:239140
STKc_RPK118_like 148..555 CDD:270728 88/421 (21%)
psk1NP_587830.1 STKc_AGC 97..350 CDD:270693 85/408 (21%)
S_TK_X 351..418 CDD:214529 4/8 (50%)
Blue background indicates that the domain is not in the aligned region.

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