DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment RPS6KL1 and ppk33

DIOPT Version :10

Sequence 1:XP_011535508.1 Gene:RPS6KL1 / 83694 HGNCID:20222 Length:603 Species:Homo sapiens
Sequence 2:NP_588234.1 Gene:ppk33 / 2539202 PomBaseID:SPCC162.10 Length:338 Species:Schizosaccharomyces pombe


Alignment Length:215 Identity:58/215 - (26%)
Similarity:90/215 - (41%) Gaps:40/215 - (18%)


- Green bases have known domain annotations that are detailed below.


Human   402 EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEP--------QCC 458
            |..::.|..|::.||..:|.:|||.||:.|.|:|||:.||.:|..|...::|..        ...
pombe   125 ESVIRIWMVELVSALIYIHSKGVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPSKSNMTV 189

Human   459 GEAVDNLYSAPE--VGGISELTEACDWWSFGSLLYELLTGMALSQSH--------------PSGI 507
            |.....:|.|||  :..:|  .:..||||.|...||.|..:....:|              .|..
pombe   190 GRVGTPVYMAPETLIHAVS--YKESDWWSLGITFYECLFQVRPFPNHLLINWIRASEEEKASSAD 252

Human   508 QAHTQLQLPE-----WLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFF-----STIQWSK 562
            :..:.|.:..     .:|:.|.|.:...|:.:..:|||...   .||::||||     .|:....
pombe   253 RLSSALHISRDKKLTTISKDARSAVMAFLEMDIKKRLGHSS---KKLQTHPFFCSISLETVSKGN 314

Human   563 LVGALVLLSG-THFPPVTDL 581
            |.......|| .:..|:.||
pombe   315 LTPIFRPKSGKVYVDPILDL 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RPS6KL1XP_011535508.1 MIT_SNX15 48..122 CDD:239140
STKc_RPK118_like 148..555 CDD:270728 49/181 (27%)
ppk33NP_588234.1 Protein Kinases, catalytic domain 29..302 CDD:473864 49/181 (27%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.