DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RMR1 and RNF13

DIOPT Version :9

Sequence 1:	NP_201417.1	Gene:	RMR1 / 836748	AraportID:	AT5G66160	Length:	310	Species:	Arabidopsis thaliana
Sequence 2:	NP_001365214.1	Gene:	RNF13 / 11342	HGNCID:	10057	Length:	381	Species:	Homo sapiens

Alignment Length:	338	Identity:	105/338 - (31%)
Similarity:	160/338 - (47%)	Gaps:	51/338 - (15%)

- Green bases have known domain annotations that are detailed below.

plant     9 LLVAAPFLSSLLRVSLATVV-------------LNSISASFADLPAKFDGSVTKNGICGALYVAD 60
            |:::|..:.::|.|.|...:             ..:.|.:|.||||:|...:...|:.|.|..:.
Human     8 LMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGLKGFLINSK 72

plant    61 PLDGCSPLLHAAASNWTQHRTTKFALIIRGECSFEDKLLNAQNSGFQAVIVYDNIDNEDLIVMKV 125
            |.:.|.|::.....:  ....|...||.|.:|:|:.|:||||.:|::|.||: |:|::|||.|..
Human    73 PENACEPIVPPPVKD--NSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVH-NVDSDDLISMGS 134

plant   126 NP----QDITVDAVFVSNVAGEILR---KYARGRDGECCLNP----PDRGSAWTVLAISFFSLLL 179
            |.    :.|.:.:||:...:...|:   .|.:|  |...|.|    |........|.|....|:|
Human   135 NDIEVLKKIDIPSVFIGESSANSLKDEFTYEKG--GHLILVPEFSLPLEYYLIPFLIIVGICLIL 197

plant   180 IVTFLLIAFFAPRHWTQWRGRHTRTIRLDAKLVHTLPCFTFTDSAHHKAGETCAICLEDYRFGES 244
            ||.|::..|...||    |.|..| :|.|.  :..||...|.....:   :.|||||::|..|:.
Human   198 IVIFMITKFVQDRH----RARRNR-LRKDQ--LKKLPVHKFKKGDEY---DVCAICLDEYEDGDK 252

plant   245 LRLLPCQHAFHLNCIDSWLTKWGTSCPVCKH-------DIRTETMSSEVHKRESPRTD-----TS 297
            ||:|||.||:|..|:|.||||...:|||||.       |..::|.||:.....:..|.     .|
Human   253 LRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSSQEENEVTEHTPLLRPLAS 317

plant   298 TSRFAFAQSSQSR 310
            .|..:|...|:||
Human   318 VSAQSFGALSESR 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RMR1	NP_201417.1	PA_C_RZF_like	28..166	CDD:239038	45/161 (28%)
RMR1	NP_201417.1	RING	231..277	CDD:238093	26/52 (50%)
RNF13	NP_001365214.1	PA_C_RZF_like	23..180	CDD:239038	45/161 (28%)
		RING-H2_RNF167	238..283	CDD:319711	25/44 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	285..381		11/46 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	71	1.000	Domainoid score	I4059
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13493
Inparanoid	1	1.050	136	1.000	Inparanoid score	I2220
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0001489
OrthoInspector	1	1.000	-	-		mtm1436
orthoMCL	1	0.900	-	-		OOG6_103040
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X670
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.730