| Sequence 1: | NP_113647.1 | Gene: | SESN2 / 83667 | HGNCID: | 20746 | Length: | 480 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_611821.1 | Gene: | Sesn / 37755 | FlyBaseID: | FBgn0034897 | Length: | 497 | Species: | Drosophila melanogaster |
| Alignment Length: | 468 | Identity: | 211/468 - (45%) |
|---|---|---|---|
| Similarity: | 281/468 - (60%) | Gaps: | 70/468 - (14%) |
- Green bases have known domain annotations that are detailed below.
|
Human 76 VDNLAVVMGLHPDYFTSFWRLHYLLLHTDGPLASSWRHYIAIMAAARHQCSYLVGSHMAEFLQTG 140
Human 141 GDPEWLLGLHRAPEKLRKLSEINKLLAHRPWLITKEHIQALLKTGEHTWSLAELIQALVLLTHCH 205
Human 206 SLSSFVFGCGILPEGDADGSP---APQA------------PTPPSE-QSSPP------------- 241
Human 242 --SRDPLNNSGGF--ESAR---------------------------DVEALMERMQQLQESLLRD 275
Human 276 EGTSQEEMESRF---ELEKSESLLVTPSADILEPSPHPDMLCFVEDPTFGYEDFTRRGAQAPPTF 337
Human 338 RAQDYTWEDHGYSLIQRLYPEGGQLLDEKFQAAYSLTYNTIAMHSGVDTSVLRRAIWNYIHCVFG 402
Human 403 IRYDDYDYGEVNQLLERNLKVYIKTVACYPEKTTRRMYNLFWRHFRHSEKVHVNLLLLEARMQAA 467
Human 468 LLYALRAITRYMT 480 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SESN2 | NP_113647.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 20..45 | ||
| PA26 | 43..479 | CDD:461375 | 208/465 (45%) | ||
| N-terminal domain, mediates the alkylhydroperoxide reductase activity. /evidence=ECO:0000269|PubMed:26612684 | 66..239 | 83/178 (47%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 222..252 | 12/60 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 272..291 | 8/21 (38%) | |||
| C-terminal domain, mediates TORC1 regulation. /evidence=ECO:0000269|PubMed:26612684 | 308..480 | 98/171 (57%) | |||
| Sesn | NP_611821.1 | PA26 | 4..496 | CDD:461375 | 208/465 (45%) |
| Blue background indicates that the domain is not in the aligned region. | |||||