DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gtf2a1 and stnB

DIOPT Version :9

Sequence 1:	NP_113568.2	Gene:	Gtf2a1 / 83602	MGIID:	1933277	Length:	378	Species:	Mus musculus
Sequence 2:	NP_001036318.2	Gene:	stnB / 4379834	FlyBaseID:	FBgn0016975	Length:	1262	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	63/287 - (21%)
Similarity:	96/287 - (33%)	Gaps:	100/287 - (34%)

- Green bases have known domain annotations that are detailed below.

Mouse    73 QHQPQQQQHHHHHHQHQQAQPQQTVPQQAQTQQVLIPASQQ--ATAPQVI--------------- 120
            |.|||.|.|.|.|    ...|:..||.|: ||.::...|.|  .|:.:::
  Fly   103 QSQPQLQSHAHPH----PPPPRPLVPPQS-TQDLISTVSSQLDETSSELLGRIPATRSPSPVSMR 162

Mouse   121 -------VPDSKLLQHMNAS--------------SITSAAATAATL----ALPAGVTPVQQLLTN 160
                   .|||.|...::.|              .:.|..|....|    |:|..|..:|..:
  Fly   163 DLHSPSPTPDSGLADLLDVSVDSGSSAHTQGIEADLISGVAGGVRLDNPFAVPTAVPNIQAAV-- 225

Mouse   161 SGQLLQVVRAANGAQYILQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQP 225
                               |..:..::|   |...|....||...   || ||..:||     :|
  Fly   226 -------------------PLPATPIKQ---PPRPPPPRPAPPRP---AP-PGQAAPQ-----RP 259

Mouse   226 QQILFTGNKTQVIPTT--------VAAPAPAQAPMPAAGQ------QQPQ---AQPAQQQAPLVL 273
            ...|...|.....|..        ..|..||:.|.|.:.:      :||.   :|||.:  |.:|
  Fly   260 PPPLAAVNPPPAAPEADDLLDMFGTTACKPAKPPPPKSKEDILSLFEQPHVPLSQPASK--PDLL 322

Mouse   274 QVDGTGDTSSEEDEDEEEDYDDDEEED 300
            . |...:|..|.:..|:|:.|.::..:
  Fly   323 H-DDLDETIGEGEPPEQEEPDTEQSNE 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gtf2a1	NP_113568.2	TFIIA_alpha_beta_like	10..>60	CDD:199899
		TFIIA	13..378	CDD:281188	63/287 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	69..108		14/34 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	247..331		17/63 (27%)
		TFIIA_alpha_beta_like	<318..378	CDD:199899
stnB	NP_001036318.2	Trypan_PARP	377..496	CDD:114603
stnB	NP_001036318.2	AP_MHD_Cterm	897..1219	CDD:299401
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1533
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030