Protein Alignment CASP3 and Decay

DIOPT Version :9

• Sequence 1: NP_001341706.1
• Gene: CASP3 / 836
• HGNCID: 1504
• Length: 277
• Species: Homo sapiens
• Sequence 2: NP_477462.1
• Gene: Decay / 42008
• FlyBaseID: FBgn0028381
• Length: 308
• Species: Drosophila melanogaster
• Alignment Length: 302
• Identity: 103/302 - (34%)
• Similarity: 167/302 - (55%)
• Gaps: 35/302 - (11%)

Human     1 MENTENSVDSKSIKNLE-----PKIIHGSES-MD------SGISLDNSYKMDYPEMGLCIIINNK 53
            |::|:.|:..:..|:.:     .||.|...| :|      |..:.:::|: :....|:.:|:|:|
  Fly     1 MDDTDFSLFGQKNKHKKDKADATKIAHTPTSELDLKRIIISRPTNEDTYE-NCARAGIALILNHK 64

Human    54 NFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVL 118
            :.   .|...|.||:.|..::..|.:...::||..:|||..||.:.:::|::||||:...||..:
  Fly    65 DV---KGQKQRVGTERDRDDMEATLQGFGFDVRTFDDLTFSEINDTLKEVAREDHSQNDCFVLAV 126

Human   119 LSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIE-------TDS 176
            :|||.||.::..:....::::.|.|.||.|::|..|||||.||||||..|:..:|       |..
  Fly   127 MSHGTEGKVYAKDMSYPVERLWNPFLGDNCKTLKNKPKLFFIQACRGANLEKAVEFSSFAVMTRE 191

Human   177 GVDDDMAC-----HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYA-------DK 229
            .|.:..|.     :.||..||.|..|||...::|:||..||||||||||.:|.|.|       :.
  Fly   192 LVPEPAAAVQPITYAIPSTADILVFYSTFDKFFSFRNVDDGSWFIQSLCRVLDQAAANEAATPEG 256

Human   230 LEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTK 271
            :|.:.:||.||||||.|::|.:.:...:..|::|..:|.|||
  Fly   257 VELLRLLTAVNRKVAYEYQSNTKNEALNQMKEMPNFMSTLTK 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CASP3	NP_001341706.1	CASc	37..277	CDD:214521	93/254 (37%)
Decay	NP_477462.1	CASc	54..302	CDD:237997	92/248 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920