Protein Alignment CASP3 and Dcp-1

DIOPT Version :9

• Sequence 1: NP_001341706.1
• Gene: CASP3 / 836
• HGNCID: 1504
• Length: 277
• Species: Homo sapiens
• Sequence 2: NP_476974.1
• Gene: Dcp-1 / 37729
• FlyBaseID: FBgn0010501
• Length: 323
• Species: Drosophila melanogaster
• Alignment Length: 298
• Identity: 105/298 - (35%)
• Similarity: 153/298 - (51%)
• Gaps: 46/298 - (15%)

Human    22 HGSESMDSGISLDNS--------------------------------------YKMDYPEMGLCI 48
            :|||:..|.|..||:                                      |.|.:...|:.:
  Fly    18 NGSENRGSFIMADNTDAKGCTPESLVVGGATAASPLPANKFVARMPVERYASEYNMSHKHRGVAL 82

Human    49 IINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSS 113
            |.|:: |.....:.||:||:|||..|::.|.||.:.|....|....:|::.:...::.||:....
  Fly    83 IFNHE-FFDIPSLKSRTGTNVDAQELKKAFENLGFAVSVHKDCKLRDILKHVGKAAELDHTDNDC 146

Human   114 FVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGV 178
            ....:|||||.|.::..:....|..|.::|....|.||.||||||.||||:|..||.||..:.||
  Fly   147 LAVAILSHGEHGYLYAKDTQYKLDNIWHYFTATFCPSLAGKPKLFFIQACQGDRLDGGITLEKGV 211

Human   179 ----DDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRV 239
                .:....:|||:.||||::|||.|||:||||..:|||::|||...|.....|.:.:.:||.|
  Fly   212 TETDGESSTSYKIPIHADFLFSYSTIPGYFSWRNINNGSWYMQSLIRELNANGKKYDLLTLLTFV 276

Human   240 NRKVATEFESFSFDAT--FHAKKQIPCIVSMLTKELYF 275
            |::||.:||| :..||  ...:|||||:.||||:.|.|
  Fly   277 NQRVALDFES-NVPATPMMDRQKQIPCLTSMLTRILRF 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CASP3	NP_001341706.1	CASc	37..277	CDD:214521	98/245 (40%)
Dcp-1	NP_476974.1	CASc	71..313	CDD:214521	97/243 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147031
Domainoid	1	1.000	199	1.000	Domainoid score	I3057
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3668
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	1	1.000	-	-		mtm8526
orthoMCL	1	0.900	-	-		OOG6_103710
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3066
SonicParanoid	1	1.000	-	-		X460
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.690