Protein Alignment Kcns3 and Shawl

DIOPT Version :9

• Sequence 1: NP_001376159.1
• Gene: Kcns3 / 83588
• RGDID: 621527
• Length: 491
• Species: Rattus norvegicus
• Sequence 2: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Alignment Length: 519
• Identity: 137/519 - (26%)
• Similarity: 222/519 - (42%)
• Gaps: 139/519 - (26%)

  Rat    14 EELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLFRY 78
            |..:.|||.|.:....::||.:.|.|||.:|         .|...:|.....||:|||:|.:|..
  Fly     4 ENRIILNVSGIRYETYKATLKKIPATRLSRL---------TEALANYDPVLNEYFFDRHPGVFTQ 59

  Rat    79 VLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSSRYQERKEESHE---KDWDQKSNDV 140
            :||:|.|||||...::|...|.:|:|:||::...::.||.|.|...::..:.   .|.....|:.
  Fly    60 ILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEK 124

  Rat   141 STDSSFEESSLFEKELEKFDELRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVLASIVAMCV- 204
            .|:........||:.|...:...:.:::.|||...:.|:....||::|..|:..:..|:::.|:
  Fly   125 PTEEQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLK 189

  Rat   205 ---------------------------------------------------------------HS 206
                                                                           :|
  Fly   190 THPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYS 254

  Rat   207 MSEF---------------------QNEDGEVDDPVLEG-------------------------- 224
            ...|                     :|.:|.:.:..:|.
  Fly   255 SGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFY 319

  Rat   225 VEIACIAWFTGELAIRLVAAPSQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVV 289
            ||:.|..||..|:.|||:.:|:..:|.|:|:|||||.:.:.||           ::.::.||:..
  Fly   320 VELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFY-----------TDVMQRMGEYT 373

  Rat   290 QILR---LMRIFRILKLARHSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEK--DE 349
            .:|.   ::||.|:.||.|||.|||.|..|.:.|..|:.||:.||.:||..|:.|.|..||  |.
  Fly   374 GLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDN 438

  Rat   350 LASSLTSIPICWWWATISMTTVGYGDTHPVTLAGKIIASTCIICGILVVALPITIIFNKFSKYY 413
            ..:...|||:..|||.::||||||||..|.|..|..:.:.|.:.|:|.:|||:.:|.:.||.:|
  Fly   439 PDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFY 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kcns3	NP_001376159.1	BTB_POZ_KCNS3	15..122	CDD:349735	37/106 (35%)
		Ion_trans	184..417	CDD:395416	88/346 (25%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	370..375		4/4 (100%)
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	35/100 (35%)
		BTB_2	7..97	CDD:280393	34/98 (35%)
		Ion_trans	307..506	CDD:278921	77/207 (37%)
		Ion_trans_2	<449..499	CDD:285168	21/49 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910