Protein Alignment MFRP and Mfrp

DIOPT Version :10

• Sequence 1: NP_113621.1
• Gene: MFRP / 83552
• HGNCID: 18121
• Length: 579
• Species: Homo sapiens
• Sequence 2: NP_001101607.1
• Gene: Mfrp / 315597
• RGDID: 1307477
• Length: 590
• Species: Rattus norvegicus
• Alignment Length: 600
• Identity: 397/600 - (66%)
• Similarity: 454/600 - (75%)
• Gaps: 31/600 - (5%)

Human     1 MKDFSDVILCMEATESSKTEFCNPAFEPESGPPCPPPVFPEDASYSVPAPWHGRRPRGLRPDCRF 65
            ||:::||.||.||.|.||||||||||:.|:||.||||...::.|.|:..|||.:|.|||:|||.|
  Rat     1 MKEYADVTLCPEAAELSKTEFCNPAFDLEAGPSCPPPALQKNVSSSLQGPWHVQRLRGLQPDCHF 65

Human    66 SWLCVLLLSSLLLLLLGLLVAIILAQLQAAPPSGASHSPLPA-GGL--------------TTTTT 115
            |.||:||||.|||||||||||:|||||||......:.:|||. |||              |||||
  Rat    66 SGLCILLLSGLLLLLLGLLVAVILAQLQATSLPRTTKNPLPTRGGLTPTGVIPSTTPNTTTTTTT 130

Human   116 TPTITTSQAAGTPKGQQESGVSPSPQSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDH 180
            ||.||         |:||:.:||:.|:||||||.||.||||||||||.|||::||||||||||..
  Rat   131 TPAIT---------GRQEAAMSPTHQTTCGGLLPGPSGFFSSPNYPDLYPPHSHCVWHIQVATGQ 186

Human   181 AIQLKIEALSIESVASCLFDRLELSPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGFG 245
            .|||||:.||.||:.:|||||||:||.|.|||||:||:.||.|:|||.|||.|.||||:.|||.|
  Rat   187 TIQLKIQVLSTESMLACLFDRLEISPAPTGPLLRMCGKTPPATVNTNTSHLRVSFVSDNDVEGSG 251

Human   246 FHAWYQAMAPGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGLQG 310
            |.|||||:|||..||.|.||.||.|:||..||||||..:|.|||||.|||||..|||||||.|.|
  Rat   252 FQAWYQAVAPGHWSCTHYEFHCDLLLCLKQDSVCDGIKDCIDGSDEANCSAKTLGCGGNLTELSG 316

Human   311 TFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSGAFSLLGR 375
            .||||:|.|.||||.||||:|.||.|:.|.|:|||||||.|.|||||||||||.|:||.||.|||
  Rat   317 VFSTPNYPQHYPHQQLCTWYIKVPVGYRIRLEFHNFSLEEQTECKFDYVEVYEASNSGTFSSLGR 381

Human   376 FCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYLAFNATENP------CGPSELSCQAGGCK 434
            |||||||.|||||.|:|.|:|:||.|||||||.|||.|.|.||:.      |||.|. ||:...:
  Rat   382 FCGAEPPSHLVSSQHQLTVIFKTDLGISSGGFLATYQAINTTESGCPWADLCGPREF-CQSRVRR 445

Human   435 GVQWMCDMWRDCTDGSDDNCSGPLFPPPELACEPVQVEMCLGLSYNTTAFPNIWVGMITQEEVVE 499
            .:|.:||:|:||.:.|:|||:..|.|..:|.|||||||||||||||||||||||||:.||.||.:
  Rat   446 ELQRICDLWKDCANDSNDNCNSHLSPQLDLTCEPVQVEMCLGLSYNTTAFPNIWVGLATQMEVTD 510

Human   500 VLSGYKSLTSLPCYQHFRRLLCGLLVPRCTPLGSVLPPCRSVCQEAEHQCQSGLALLGTPWPFNC 564
            :|.||||||||||||.|||.|||||.||||.||::||||||||||||.||||.|||||.||||||
  Rat   511 ILRGYKSLTSLPCYQTFRRFLCGLLEPRCTSLGTILPPCRSVCQEAEQQCQSSLALLGIPWPFNC 575

Human   565 NRLPEAADLEACAQP 579
            ||||..|.||||:||
  Rat   576 NRLPVPASLEACSQP 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFRP	NP_113621.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	100..143		21/57 (37%)
		CUB	144..252	CDD:238001	78/107 (73%)
		LDLa	260..294	CDD:238060	21/33 (64%)
		CUB	301..411	CDD:238001	81/109 (74%)
		LDLa	421..454	CDD:238060	14/32 (44%)
		CRD_FZ	466..579	CDD:143549	92/112 (82%)
Mfrp	NP_001101607.1	CUB	150..258	CDD:238001	78/107 (73%)
		LDLa	266..300	CDD:238060	21/33 (64%)
		CUB	307..419	CDD:238001	83/111 (75%)
		CRD_FZ	476..590	CDD:143549	92/113 (81%)