Protein Alignment TAAR8 and mAChR-C

DIOPT Version :9

• Sequence 1: NP_444508.1
• Gene: TAAR8 / 83551
• HGNCID: 14964
• Length: 342
• Species: Homo sapiens
• Sequence 2: NP_572358.1
• Gene: mAChR-C / 31626
• FlyBaseID: FBgn0029909
• Length: 371
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 91/342 - (26%)
• Similarity: 149/342 - (43%)
• Gaps: 62/342 - (18%)

Human     9 VVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGS-------------LLAVFGNLLVMTSVLHFK 60
            ||...::..|.:  |||..     |...|.|||:             :|.:.||:|.:.:|...:
  Fly    22 VVPFLWQHQNAT--ETPTE-----ITLQATSFGAGHLLWLAINAFLFVLILGGNILTIVAVRTCR 79

Human    61 QLHSP-TNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAF------CYSS 118
            .|.|. :|..|.|||.:||.||: .:.:.:|      :|.|:....:...|.:.|      |..|
  Fly    80 HLRSVISNLFILSLAVSDFCVGL-ALPYHLV------FYMGSDIGAMRGPCLLRFFLLICACCVS 137

Human   119 VLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGA------VFYTGVNDDGLE 177
            :|.|..|.:||||.|...|.|....|..|:...|..:|.|     ||      ||:....|....
  Fly   138 MLTLISIAVDRYIAVVYALHYRRYMTRRVAYSIIIFNWCL-----GALVALLPVFWNRWPDAQAC 197

Human   178 EL--VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESS 240
            |.  |.|...:.|   :::.|:|:|        .:.|.::|.:|...|.:||:::.  .|.|.::
  Fly   198 EFDEVLAPGYIAG---VITPGFVII--------WICMFLVYWRIMREASKQALRLR--QSVVYNT 249

Human   241 SESYKIR--VAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNS 303
            .|:..:|  :...:.|:.:.:...:..|.:.||||....:...|....:.:.||:.....|..||
  Fly   250 DEATTMRNLLLHPDWKSVQIVVFIMGCFTLCWLPYFCVAIAQLFSICQSSSMIYKTTFSLAIANS 314

Human   304 AMNPLIYALFYPWFRKA 320
            |:||:||:.....||:|
  Fly   315 ALNPIIYSWKNSGFRRA 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAAR8	NP_444508.1	7tm_1	48..310	CDD:278431	74/278 (27%)
mAChR-C	NP_572358.1	7tm_4	61..332	CDD:304433	80/296 (27%)
		7tm_1	67..321	CDD:278431	74/278 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24249
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010