Protein Alignment TAAR8 and chrm1

DIOPT Version :9

• Sequence 1: NP_444508.1
• Gene: TAAR8 / 83551
• HGNCID: 14964
• Length: 342
• Species: Homo sapiens
• Sequence 2: XP_004913717.1
• Gene: chrm1 / 100490434
• XenbaseID: XB-GENE-22061118
• Length: 521
• Species: Xenopus tropicalis
• Alignment Length: 490
• Identity: 101/490 - (20%)
• Similarity: 166/490 - (33%)
• Gaps: 185/490 - (37%)

Human     1 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSP 65
            :|||.::.     |:.:.|..:      ...|::.......||:.|.||:||:.:......|.:.
 Frog    28 LTSNATEE-----YDPLGGHAV------WEVVLIVITTGILSLVTVIGNVLVLLAFKVNSDLKTV 81

Human    66 TNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRY 130
            .|:.:.||||||.::|...|.......|...|..|...|.|....|.....:||::|..|..|||
 Frog    82 NNYFLLSLACADIIIGALSMNLYTTYIVMGRWALGPVSCDLWLALDYVASNASVMNLLIISFDRY 146

Human   131 IVVTDPLVYATKFTVSVSGICISVSWILP-LTYSGAVFY----TGVNDDGLEELVSALNCV--GG 188
            ..:|.||.|..|.|...:.|.|.::|.:. :.::.|:.:    .|      |..|.|.:|.  ..
 Frog   147 FSITRPLTYRAKRTPRRAAIMIGMAWFISFVLWAPAIIFWQYIVG------ERTVEATDCYIQFF 205

Human   189 CQIIVSQGWVLIDFLLFFIPTLVMIILYSKIF--------------------------------- 220
            .|.|::.|..:   ..|::|..:|||||.:::
 Frog   206 SQPIITFGTAI---AAFYLPVTIMIILYWRVYRETENRSKELAGLQGSGTDHTSHPLALGSVRSG 267

Human   221 ------------------------------------------------------------LIAKQ 225
                                                                        |.:..
 Frog   268 SSSGAGESERLSRGQRTVPRAKQGCCFPRQLTSNPSLRSYPEHRSNGSCNTMEDAASADSLSSSS 332

Human   226 QA-----------------------------------------IKIETTSSKVESSSESYKIRV- 248
            :|                                         |:.||...|.|.:.::.:.:|
 Frog   333 EAEDRPYEMKNICSAVIRLPMVSSVVGTPKGSRGSSDTLGRGDIEAETNGGKSEVTRKTSRAQVT 397

Human   249 --------AK---------------RERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAY 290
                    ||               :|:||||||...:|||:::|.||.:.:|:..|.....|..
 Frog   398 ALPSTIIRAKSEKNHHGKRKSNSLIKEKKAAKTLSAILLAFILTWTPYNIMVLVSTFCPDCVPKK 462

Human   291 IYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLIL 325
            ::|:..|..|.||.:||:.|||....||:..|::|
 Frog   463 LWELGYWLCYVNSTVNPMCYALCNRSFRRTFKMLL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAAR8	NP_444508.1	7tm_1	48..310	CDD:278431	85/426 (20%)
chrm1	XP_004913717.1	7tmA_mAChR_M1	48..493	CDD:341356	94/453 (21%)
		TM helix 1	49..75	CDD:341356	7/25 (28%)
		TM helix 2	82..108	CDD:341356	9/25 (36%)
		TM helix 3	120..150	CDD:341356	10/29 (34%)
		TM helix 4	162..185	CDD:341356	4/22 (18%)
		TM helix 5	207..236	CDD:341356	10/31 (32%)
		TM helix 6	422..452	CDD:341356	14/29 (48%)
		TM helix 7	461..486	CDD:341356	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910