DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TAAR8 and taar13e

DIOPT Version :9

Sequence 1:	NP_444508.1	Gene:	TAAR8 / 83551	HGNCID:	14964	Length:	342	Species:	Homo sapiens
Sequence 2:	NP_001076512.1	Gene:	taar13e / 100034381	ZFINID:	ZDB-GENE-041014-70	Length:	341	Species:	Danio rerio

Alignment Length:	332	Identity:	139/332 - (41%)
Similarity:	212/332 - (63%)	Gaps:	6/332 - (1%)

- Green bases have known domain annotations that are detailed below.

Human    11 QLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFKQLHSPTNFLIASLAC 75
            |.|:..||.||::..:...::.::|...:....:.:.||.:|:.|:.|||||.:|||.|:.|||.
Zfish    12 QFCFPAVNNSCLKGTHHVSTQTVVYLVLASAMTVTILGNSVVIISIAHFKQLQTPTNILVMSLAL 76

Human    76 ADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYA 140
            ||.|:|:.||.|||:|:|:.|||:|..||.|||..|:.....|:.||.||.:||:..|..||.|.
Zfish    77 ADLLLGLVVMPFSMIRSVDGCWYYGETFCLLHSSFDMFLTSVSIFHLIFIAVDRHQAVCFPLQYP 141

Human   141 TKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLL- 204
            |..|:.|:.:.:.:||.:...||..:.|:..|.:||||.:.::.|:|||.::.:..|..||.|:
Zfish   142 TMITIPVAWVMVIISWSMAAFYSYGLVYSKANVEGLEEYIESIYCMGGCTLLFNALWGAIDTLVA 206

Human   205 FFIPTLVMIILYSKIFLIAKQQAIKI-ETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVI 268
            ||:|..|||.||::||:|||:.|.|: |......|:..:|.:    :.|||||||||:.|.||||
Zfish   207 FFLPCFVMIGLYARIFMIAKKHARKLGEANQHDNENLFKSSR----RSERKAAKTLGIVVGAFVI 267

Human   269 SWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKAS 333
            .|||:.::.::|.::.|.||..::|...|..|.|||:||:||.||||||||.:.||::..:.:.:
Zfish   268 CWLPFFINSMMDPYINFSTPGVLFEAFVWLGYMNSAINPIIYGLFYPWFRKTLYLIITLRMFEPN 332

Human   334 SSTISLF 340
            ||.|::|
Zfish   333 SSDINVF 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TAAR8	NP_444508.1	7tm_1	48..310	CDD:278431	116/263 (44%)
taar13e	NP_001076512.1	7tm_4	43..>269	CDD:304433	101/229 (44%)
taar13e	NP_001076512.1	7tm_1	49..309	CDD:278431	116/263 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I36869
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24249
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.970