Protein Alignment DNAL1 and ODA-Dnal1

DIOPT Version :10

• Sequence 1: NP_113615.2
• Gene: DNAL1 / 83544
• HGNCID: 23247
• Length: 190
• Species: Homo sapiens
• Sequence 2: NP_610483.1
• Gene: ODA-Dnal1 / 35962
• FlyBaseID: FBgn0033408
• Length: 188
• Species: Drosophila melanogaster
• Alignment Length: 188
• Identity: 110/188 - (58%)
• Similarity: 140/188 - (74%)
• Gaps: 1/188 - (0%)

Human     1 MAKATTIKEALARWEEKTGQRPSEAKEIKLYAQIPPIEKMDASLSMLANCEKLSLSTNCIEKIAN 65
            |:|||||||||.||||:..|....||.|.|..|.|||||||::|..|..||::|:|||.||||..
  Fly     1 MSKATTIKEALKRWEEREQQNSLTAKVIDLQFQWPPIEKMDSTLGTLVQCERISMSTNMIEKIFG 65

Human    66 LNGLKNLRILSLGRNNIKNLNGLEAVGDTLEELWISYNFIEKLKGIHIMKKLKILYMSNNLVKDW 130
            |:|:|.|::|||.||.||.::|||||.:||||||:|||.|||:||:..:|.||:||:||||:|||
  Fly    66 LSGMKCLKVLSLSRNYIKQISGLEAVAETLEELWLSYNLIEKIKGLTGLKCLKVLYISNNLIKDW 130

Human   131 AEFVKLAELPCLEDLVFVGNPLEEKHSAENNWIEEATKRVPKLKKLDGTPVIKGDEEE 188
            :||.:|||:..|||||.|||||.|... |..|..|..||:|.::||||.||:..:|.:
  Fly   131 SEFNRLAEIESLEDLVVVGNPLSEGLD-EPTWRAECIKRLPTIRKLDGEPVVLNEEPQ 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAL1	NP_113615.2	PPP1R42	37..181	CDD:455733	85/143 (59%)
		LRR 1	49..70		12/20 (60%)
		leucine-rich repeat	50..71	CDD:275378	12/20 (60%)
		LRR 2	71..92		12/20 (60%)
		leucine-rich repeat	72..90	CDD:275378	10/17 (59%)
		LRR 3	94..115		14/20 (70%)
		leucine-rich repeat	95..116	CDD:275382	13/20 (65%)
		LRR 4	116..137		13/20 (65%)
		leucine-rich repeat	117..140	CDD:275382	16/22 (73%)
		leucine-rich repeat	142..172	CDD:275382	16/29 (55%)
ODA-Dnal1	NP_610483.1	PPP1R42	37..180	CDD:455733	85/143 (59%)
		leucine-rich repeat	50..71	CDD:275380	12/20 (60%)
		leucine-rich repeat	95..116	CDD:275380	13/20 (65%)
		leucine-rich repeat	117..141	CDD:275380	16/23 (70%)