Protein Alignment DNAL1 and tilB

DIOPT Version :10

• Sequence 1: NP_113615.2
• Gene: DNAL1 / 83544
• HGNCID: 23247
• Length: 190
• Species: Homo sapiens
• Sequence 2: NP_608460.1
• Gene: tilB / 33130
• FlyBaseID: FBgn0014395
• Length: 395
• Species: Drosophila melanogaster
• Alignment Length: 177
• Identity: 45/177 - (25%)
• Similarity: 79/177 - (44%)
• Gaps: 40/177 - (22%)

Human     7 IKEALARWEEKTGQR-PSEAKEIKLYAQIPPIEKMDASLSMLANCEKLSLSTNCIEKIANLNGLK 70
            |.|.|.|.:.:..:| .|..:||.|:.:  .||.::...:...:.:.|.|.:|.|.::.||:.||
  Fly     4 ITEELVRKKSEHNERLISTLEEISLHQE--DIEVIEHIQNWCRDLKILLLQSNLIARLENLHKLK 66

Human    71 NLRILSLGRNNIKNLNGLEAVGDTLEELWISYNFIEKLKGIHIMKKLKILYMSNNLVKDWAEFVK 135
            .|..|::..|||:.:..||.. ::|.:|.::.|||.:|..:
  Fly    67 RLEYLNVAINNIERVENLEGC-ESLSKLDLTLNFIRELTSV------------------------ 106

Human   136 LAELPC----LEDLVFVGNP-LEEKHSAENNWIEEATKRVPKLKKLD 177
              |..|    |.:||.:||| ::..|     :.:.....:|:|..||
  Fly   107 --ESLCGNYNLRELVLIGNPCVDYPH-----YRDYVVATLPQLNSLD 146

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAL1	NP_113615.2	PPP1R42	37..181	CDD:455733	36/146 (25%)
		LRR 1	49..70		6/20 (30%)
		leucine-rich repeat	50..71	CDD:275378	7/20 (35%)
		LRR 2	71..92		7/20 (35%)
		leucine-rich repeat	72..90	CDD:275378	6/17 (35%)
		LRR 3	94..115		6/20 (30%)
		leucine-rich repeat	95..116	CDD:275382	6/20 (30%)
		LRR 4	116..137		0/20 (0%)
		leucine-rich repeat	117..140	CDD:275382	1/22 (5%)
		leucine-rich repeat	142..172	CDD:275382	7/30 (23%)
tilB	NP_608460.1	PPP1R42	<23..155	CDD:455733	39/158 (25%)
		leucine-rich repeat	23..45	CDD:275378	5/23 (22%)
		leucine-rich repeat	46..67	CDD:275378	7/20 (35%)
		leucine-rich repeat	68..89	CDD:275378	7/21 (33%)
		leucine-rich repeat	90..114	CDD:275378	8/49 (16%)