DRSC/TRiP Functional Genomics Resources

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Protein Alignment ODAD4 and F32D1.3

DIOPT Version :9

Sequence 1:NP_113609.1 Gene:ODAD4 / 83538 HGNCID:25280 Length:672 Species:Homo sapiens
Sequence 2:NP_504200.1 Gene:F32D1.3 / 178832 WormBaseID:WBGene00017983 Length:774 Species:Caenorhabditis elegans


Alignment Length:330 Identity:68/330 - (20%)
Similarity:125/330 - (37%) Gaps:91/330 - (27%)


- Green bases have known domain annotations that are detailed below.


Human   220 TVEDLIMTGINYLDTHSNFWRQQKPIYARERDRKLMQEKWLRDHKRRPS-QTAHYILKSLEDIDM 283
            |.|.|..:.:....|.:|.  ....:|..::..:|.:..:.:..||:.: ..|.|.|..|..   
 Worm   421 TEESLFKSALEVNPTKANM--NLGYVYTTQKKYELAKYHYRQALKRQGNLADAWYNLGILTS--- 480

Human   284 LLTSGSAEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMEAALQSHRKDL- 347
             .||.::.||:...:..|:....:....:        ||...:.:|    |...||.....|.| 
 Worm   481 -KTSNNSNGSIHCYQMALQSRSTYAAAHL--------NLALLLHDA----GHHMAAFSHLDKCLN 532

Human   348 ---EIAKEYDLPDAKSRA--LDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKT-WLFHEIGRC 406
               |..|.|.: :.|::|  ..|.||:..:.|.|..||:.:|..:.|.....|.| .:.:.:|.|
 Worm   533 NTGEFLKFYHV-NRKTQATCAFNKGRLLQKSGNFHVAIENFELALKLGGPHFEHTPSVLNSMGTC 596

Human   407 YLEL--------------------------------DQAWQAQNYGEKSQQCAEEEGDIEWQLNA 439
            |.||                                :::::.:|...|:...|.|        :.
 Worm   597 YNELGDEQSAEKFFGKAIGENHVNSYLTMAHLKIRQNRSFEVENLLRKAMTLAPE--------SV 653

Human   440 SVL--VAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAIISALD----DANKGIIRELRKT- 497
            :||  :|.|:..::::..::..:.|||.                 ||    |:.:||...|::| 
 Worm   654 TVLQNIALAEFHMQNYNRSLLFYRKALH-----------------LDPTHLDSLQGIANLLQQTQ 701

Human   498 NYVEN 502
            |:||:
 Worm   702 NHVES 706

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ODAD4NP_113609.1 TPR 1. /evidence=ECO:0000255 13..46
TPR_11 16..78 CDD:290150
TPR repeat 16..41 CDD:276809
TPR repeat 46..76 CDD:276809
TPR 2. /evidence=ECO:0000255 48..80
TPR_11 49..112 CDD:290150
TPR 3. /evidence=ECO:0000255 81..114
TPR repeat 81..109 CDD:276809
TPR 4. /evidence=ECO:0000255 275..311 7/35 (20%)
TPR repeat 311..349 CDD:276809 8/41 (20%)
TPR_12 316..385 CDD:290160 20/74 (27%)
TPR 5. /evidence=ECO:0000255 320..353 10/36 (28%)
TPR 6. /evidence=ECO:0000255 360..393 10/34 (29%)
TPR repeat 360..385 CDD:276809 8/26 (31%)
TPR_12 361..429 CDD:290160 20/102 (20%)
TPR 7. /evidence=ECO:0000255 397..430 9/65 (14%)
TPR_12 398..468 CDD:290160 16/103 (16%)
TPR repeat 431..465 CDD:276809 6/35 (17%)
TPR 8. /evidence=ECO:0000255 437..470 7/34 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 527..672
F32D1.3NP_504200.1 DUF1736 244..316 CDD:369859
TPR repeat 436..464 CDD:276809 3/29 (10%)
TPR 448..748 CDD:223533 62/301 (21%)
TPR repeat 469..498 CDD:276809 8/32 (25%)
TPR repeat 504..531 CDD:276809 7/38 (18%)
TPR repeat 537..578 CDD:276809 12/41 (29%)
TPR repeat 587..614 CDD:276809 5/26 (19%)
TPR repeat 619..647 CDD:276809 2/27 (7%)
TPR repeat 655..681 CDD:276809 6/25 (24%)
TPR repeat 686..716 CDD:276809 8/21 (38%)
TPR repeat 721..748 CDD:276809
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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