DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RIN3 and amfr

DIOPT Version :9

Sequence 1:	NP_001190515.1	Gene:	RIN3 / 835219	AraportID:	AT5G51450	Length:	595	Species:	Arabidopsis thaliana
Sequence 2:	NP_001017083.1	Gene:	amfr / 549837	XenbaseID:	XB-GENE-923086	Length:	635	Species:	Xenopus tropicalis

Alignment Length:	561	Identity:	138/561 - (24%)
Similarity:	226/561 - (40%)	Gaps:	161/561 - (28%)

- Green bases have known domain annotations that are detailed below.

plant    53 LLSSHTTIALLASFVLNIYILLVLSLKTLFFGDLYAIETRKLVERLANYIIYKGTFLPFVV-PRT 116
            |:|....:.:|.:.|..:.:|:...::.:.||.|...|.:.|.::..|:|.||..|:..|: .:|
Frog    69 LVSDSLGVWVLVNTVCCLLMLIAKLIQHVVFGPLRVGERQHLKDKFWNFIFYKFIFIFGVLNVQT 133

plant   117 VFQGVLWTIWLTVLCTLKMFQALARDRLDRLNASPSSTPWTYFRVYSALFMVLSTDLCWIKLSLM 181
            |.:.|||.:|...|..|.:...|.:||.:.|:.||::....:.||                  |:
Frog   134 VEEVVLWFLWFAGLLFLHLMVQLCKDRFEYLSFSPTTPMSCHMRV------------------LV 180

plant   182 IYNTVGSSVYLLLLFEPCGIAFETLQALLIHGFQLLDMWINHLAVKNSDCQRSKFYDSMTAGSLL 246
            :.|        ::|...||:|.....|...||       ::.||...::|.   ...:.|...:|
Frog   181 LLN--------IMLLACCGLAVLCAIAGYTHG-------MHTLAFMAAECM---LVTTRTTHVVL 227

plant   247 ---------------EWKGLLNRNLGFFLDMATLVMALGHYLHIWWLHGMAFHLVDAVLFLNIRA 296
                           |.||.......|.::::.|.:.|.|::|:.....:...:...|:|:.:|.
Frog   228 RYVIHLWDLNHEGTWEGKGTYVYYTDFVMELSHLSIDLMHHIHMLLFGNIWLSMASLVIFMQLRH 292

plant   297 LLSSILKRI---KGYIKLRVALGALHAALLDATSEELRDYDDECAICREPMAKAKRLHCNHLFHL 358
            |.....:||   |.|:::   :|.:.|....||.|||....|:||||.:.|..|::|.|.||||.
Frog   293 LFHEFQRRIRRHKNYLRV---VGNMEAHFAVATPEELEANSDDCAICWDSMQSARKLPCGHLFHN 354

plant   359 GCLRSWLDQGLNEVYSCPTCRKPLFVGRTESEANPSRGEVSSDEHLARQFERQNNSVHALTTGMF 423
            .||||||:|..    ||||||..|      :.|:.:|..|..        :|:|...:|:...:
Frog   355 SCLRSWLEQDT----SCPTCRMSL------NMADGTRTRVEQ--------QRENQDQNAVPLAV- 400

plant   424 PTETPNFTESDPWRLAFLNGISSSHLFLMPYRNSEVDPSWLQTWSDQGVDVVGSSAGSRSVGLGQ 488
                   ||..| ||...|     |.|   :.:.....|||.::|
Frog   401 -------TEGRP-RLNHHN-----HFF---HFDGSRFASWLPSFS-------------------- 429

plant   489 VQLMMRHLASVGEGSAQTTLDDASWGLWPMNPSQASTSSTYVPPGAGGRTGGLHLRTVSRAANNM 553
            |::|  |..::                  :..:|||.|
Frog   430 VEVM--HTTNI------------------LGLAQASNS--------------------------- 447

plant   554 ASILAMAETVREVLPHVPDEIIFQDLQRTNSVSVTVNNLLQ 594
             .:.|||..|.::.|.||..::.||||.|.||.:|.:|:|:
Frog   448 -QLNAMARQVLDMFPQVPYHLVLQDLQLTRSVEITTDNILE 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RIN3	NP_001190515.1	HRD1	57..>382	CDD:227568	93/343 (27%)
		RING	336..382	CDD:238093	25/45 (56%)
		CUE_RIN3_plant	556..593	CDD:270605	16/36 (44%)
amfr	NP_001017083.1	HRD1	75..>374	CDD:227568	93/341 (27%)
		RING-H2_AMFR	331..374	CDD:319369	26/46 (57%)
		RING-H2 finger (C3H2C3-type)	333..370	CDD:319369	22/40 (55%)
		CUE_AMFR	450..490	CDD:270604	17/38 (45%)
		G2BR	564..589	CDD:375868
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	168	1.000	Inparanoid score	I1858
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D897451at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3836
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060